摘要
目的:提取甘草中抗癌活性物质角鲨烯,对提取溶剂、提取方法及工艺参数进行选择优化。方法:以浸膏得率和角鲨烯含量为评价指标,对提取溶剂和提取方法进行选择,并通过单因素实验和正交试验对实验参数进行优化。结果:以石油醚为提取溶剂,采用超声波法,在50℃下超声处理40min。在此条件下,浸膏得率为0.78%,浸膏中角鲨烯含量为0.33%。结论:超声波法提取简便易行,优化后的工艺能有效提取甘草中的角鲨烯,为甘草综合利用提供了依据。
Objective：This article was to study the extraction of bioactive substance squalene from Glycyrrhiza uralensis,and to optimize its technic extracting technique.Methods：The optimum extraction process was selected by One-factor experimental design and orthogonal design using the dry extract rate and the squalene content as evaluation index to compare the effect of extraction.Results：The optimum extraction process was that added 15 times petroleum ether and soaked for 10 hours and then sonicated for 40 minutes under 50℃.Under the optimized condition,the dry extract rate was 0.78% and contained 0.33% squalene.Conclusion：The ultrasonic method is simple for extracting squalene from Glycyrrhiza uralensis,and the optimization extraction technology is efficient.It can provide the basis for comprehensive use of glycyrrhiza.
出处
《辽宁中医杂志》
CAS
北大核心
2011年第10期2047-2049,共3页
Liaoning Journal of Traditional Chinese Medicine
基金
宁夏回族自治区科技攻关计划项目(KGX-07-09-06)
辽宁自然科学基金项目(NZ1013)
关键词
甘草
角鲨烯
提取工艺
综合利用
Glycyrrhiza uralensis
squalene
extraction
comprehensive utilization
