摘要
目的探讨血清和龈沟液中白细胞介素(IL)-6含量与绝经妇女牙周炎的关系。方法选择2010年8月至2011年1月广东省深圳市龙岗中心医院耳鼻咽喉科分院口腔科牙周炎初诊绝经女性患者20例(患牙20颗),检查并记录治疗前和治疗后4周患牙的牙龈指数(GI)、牙周探诊深度(PD)、附着丧失(AL),采集治疗前和治疗后4周患者的血清和患牙龈沟液并用酶联免疫吸附法(ELISA)测定其IL-6质量浓度。结果牙周基础治疗后患牙龈沟液中IL-6质量浓度较治疗前明显降低,差异有统计学意义(t=3.015,P<0.01);患者血清中IL-6阳性率在治疗前后的差异无统计学意义(χ2=1.056,P>0.05)。治疗后各项牙周指标(GI、PD、AL)均较治疗前降低,差异有统计学意义(均P<0.05)。结论牙周基础治疗对患牙周炎的绝经妇女牙周局部IL-6含量有影响,而对其血液IL-6含量无影响。
Objective To investigate the relationship of IL-6 level in gingival crevicular fluid and serum with periodontitis in postmenopausal women. Methods Select 20 teeth from 20 periodontitis in postmenopausal women from August 2010 to January 2011, collect blood and gingival crevicular fluid in patients before treatment and record clinical indices, and then collect blood and gingival crevicular fluid and record clinical indices a month later. Use enzyme-linked immunosorbent assay to detect IL-6 level. Results After periodontal treatment the IL-6 level in gingival crevicular fluid was significantly lower, and clinical indices changed significantly, but the IL-6 level in serum did not change significantly. Conclusion Periodontal treatment could affect local IL-6 level in postmenopausal women, while no efl＇ect on IL-6 levels in serum.
出处
《中国实用口腔科杂志》
CAS
2011年第9期544-545,共2页
Chinese Journal of Practical Stomatology
关键词
绝经妇女
牙周炎
牙周基础治疗
龈沟液
血清
IL-6
postmenopausal women
periodontitis
periodontal treatment
gingival crevicular fluid
serum
IL-6
