中药对多囊卵巢综合征痰湿证性激素及性激素结合球蛋白表达的干预性研究被引量：14

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摘要目的:探讨启宫丸方对多囊卵巢综合征(PCOS)痰湿证性激素及性激素结合球蛋白(SHBG)表达的干预作用,从而为PCOS的中医规范化诊治提供依据。方法:以45例正常育龄妇女为对照组6,5例PCOS患者为观察组,治疗前各组化学发光法测定血清FSH、LH、PRL、E2、T、DHEA-S水平及SHBG水平,观察组应用启宫丸治疗2个月后复查上述指标。结果:(1)治疗前两组性激素比较:观察组LH、T、DHEA-S值与对照组比较均有显著性升高(P<0.05);(2)治疗前两组SH-BG比较:观察组与对照组比较有极显著性差异(P<0.01);(3)治疗后观察组T、DHEA-S水平显著性降低,SHBG水平显著性升高,LH水平没有显著性改变。结论:多囊卵巢综合征痰湿证DHEA-S、SHBG等指标具有特征性表达,与胰岛素抵抗有明显的相关性;启宫丸可以明显改善PCOS患者的胰岛素抵抗状态。

作者张宁

机构地区山东中医药大学附属医院

出处《贵阳中医学院学报》 2011年第5期43-45,共3页 Journal of Guiyang University of Chinese Medicine

基金 2010年国家自然科学基金项目项目编号(81072758)

关键词多囊卵巢综合征痰湿胰岛素抵抗性激素结合球蛋白中药

分类号 R711.75 [医药卫生—妇产科学]

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参考文献9

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二级参考文献17

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