摘要
目的:探索Tourette综合征(TS)的中西医结合治疗,以期寻求有效的治疗方法。方法:将62例Tourette综合征患者随机分为2组,对照组用氟哌啶醇治疗0.05 g.kg-1.d-1,分3次口服,中西医结合组在健脾平肝的基础上,同时服用氟哌啶醇治疗0.05 g.kg-1.d-1,分3次口服。2个疗程后进行评定。治疗前后使用耶鲁抽动抽动程度综合量表(YGTSS)及治疗中需处理的不良反应症状量表(TESS)评估其疗效及不良反应。结果:两组比较总有效率有显著差异(P<0.05);两组治疗后TGTSS评分均较治疗前降低,具有显著性差异(P<0.01)。治疗后中西医结合组评分低于对照组,差异有统计意义(P<0.05);中医症候积分两组治疗前后统计均有显著性差异(P<0.01),治疗后两组比较也有显著性差异(P<0.01)。结论:健脾平肝法能提高治疗TS的疗效。
Objective： To explore therapeutic efficiency of Tourette＇s syndrome by therapy of combining traditional Chinese and western medicine.Method： The patients with Tourette＇s syndrome were randomly divided into two groups,the control group was orally treated with haloperidol 0.05 g·kg-1·d-1,tid.the integration group of traditional Chinese and western medicine was orally treated with haloperidol 0.05 g·kg-1·d-1,tid on the basis of Jianpi-pinggan After 2 Course of treatment,the yale global tic severity scale（YGTSS） and treatment emergent symptom scale（TESS） were applied to assess the efficacy and adverse reaction of treatment.Result： The total effective rate were significantly different between two groups（P0.05）.TGTSS score for the two groups was lower（P0.01）compared with prior treatment.For the integration group of traditional Chinese and western medicine score was lower than the control group（P0.05） after the treatment.For symptoms of Chinese medicine score showed a significantly different after treatment for two groups（P0.01）.After treatment,there are was significant difference between the two groups（P0.01）.Conclusion： Jianpi-pinggan has effects on TS.
出处
《中国实验方剂学杂志》
CAS
北大核心
2011年第20期272-275,共4页
Chinese Journal of Experimental Traditional Medical Formulae
