摘要
血小板活化因子（platelet—activating factor，PAF）是一种具有多种生理功能的内源性磷脂，其生物学活性极强，在体内多种生理、病理过程中均可发挥作用。1970年，Henson等发现白细胞可刺激血小板分泌一种“可溶性因子”；1972年，Benveniste等在家兔中发现该种“可溶性因子”可由IgE致敏的嗜碱性粒细胞释放出来，具有活化血小板的作用，遂首次将其命名为PAF，
出处
《中国心血管杂志》
2011年第5期396-398,共3页
Chinese Journal of Cardiovascular Medicine
参考文献38
-
1Henson PM. Release of vasoactive amines from rabbit platelets induced by sensitized mononuclear leukocytes and antigen. J Exp Med, 1970, 131: 287-306.
-
2Benveniste J, Henson PM, Cochrane CG. Leukocyte-dependent histamine release from rabbit platelets: the role of IgE, basophils, and platelet-activating factor. J Exp Med, 1972, 136 : 1356-1377.
-
3Montrucchio G, Alloatti G, Camussi G. Role of platelet-activating factor in cardiovascular pathophysiology. Physiol Rev, 2000, 80 : 1669-1699.
-
4Harayama T,Shindou H, Ogasawara R, et al. Identification of a novel noninflammatory biosynthetic pathway of platelet-activating factor. J Biol Chem, 2008, 283 : 11097-11106.
-
5Honda Z, Nakamura M, Miki I, et al. Cloning by functional expression of platelet-activating factor receptor from guinea-pig lung. Nature, 1991, 349: 342-346.
-
6Chao W, Olson MS. Platelet-activating factor: receptor and signal transduction. Biochem J, 1993, 292: 617-629.
-
7Chu WF, Sun HL, Dong DL, et al. Increasing Intracellular calcium of guinea pig ventricular myocytes induced by platelet activating factor through IP3 pathway. Basic Clin Phannacol Toxicol, 2006, 98: 104-109.
-
8Muirhead EE, Byers LW, Desiderio DM, et al. Antihypertensive lipids from the kidney : alkyl ether analogs of phosphatidylcholine. Federation Proc, 1981, 40: 2285-2290.
-
9Szabo C, Wu CC, Mitchell JA, et al. Platelet-activating factor contributes to the induction of nitric oxide synthase by bacterial lipopolysaccharide. Circ Res, 1993, 73: 991-999.
-
10Bourgain RH,Maes L, Braquet P, et al. The effect of 1-O-alkyl- 2-acetyl-sn-glycero-3- phosphocholine (PAF-acether) on the arterial wall. Prostaglandins, 1985, 30: 185-195.
二级参考文献1
-
1Karim A. Qayumi,John C. English,Elizabeth J.E. Feeley,Ahmed Poostizadeh,Maryam Nikbakht-Sangari. A New Platelet-Activating Factor Antagonist (CV-6209) in Preservation of Heart and Lung for Transplantation[J] 1997,Cardiovascular Drugs and Therapy(6):777～785
同被引文献23
-
1王旋,张慧灵,顾振纶,秦正红.银杏内酯药理作用的研究进展[J].中草药,2005,36(11):1741-1744. 被引量：63
-
2王刚,孙备,孟庆辉,姜洪池.血小板活化因子乙酰水解酶对重症急性胰腺炎影响的实验研究[J].中国普通外科杂志,2005,14(11):834-837. 被引量：2
-
3谢幸,苟文丽.妇产科学.8版.北京:人民卫生出版社,2013:55-56.
-
4Sibai B, Dekker G, Kupferminc M. Preeclampsia. Lancet, 2005, 365:785-799.
-
5Tanaka Y, Nagai Y, Kuroishi T, et al. Stimulation of Ly- 6G on neutrophils in LPS - primed mice induces platelet - acti- vating factor (PAF) - mediated anaphylaxis - like shock. J LeukocBiol, 2012, 91: 485-494.
-
6Thivierge M, Rola- Pleszczynski M. Enhancement of pulmonary natural killer cell activity by platelet activating factor: mechanisms of activation involving Ca^2+ , protein kinase C, and lipooxygena: products Am Rev Respir Dis, 1991, 144:272 - 277.
-
7Tjoelker LW, Wilder C, Eberhardt C, et al. Anti- inflam- matory properties of a platelet - activating acetylhydrolase factor. Nature, 1995, 374: 549-553.
-
8李国信,夏素霞,刘胜利,王月敏,唐思.银杏内酯B注射液在健康人体的药代动力学[J].中国临床药理学杂志,2008,24(2):118-121. 被引量：10
-
9陈国伟,唐移忠,陈江鸿,黄英,钟华.早发型重度子痫前期患者发病孕龄及终止妊娠时机对围产结局的影响[J].实用医学杂志,2009,25(3):389-391. 被引量：14
-
10林力华,何晓宇.单核细胞趋化蛋白-1与子痫前期[J].吉林医学,2011,32(2):325-327. 被引量：5
引证文献2
-
1姜晶,张华伟,唐萍.血小板活化因子乙酰水解酶与子痫前期的相关性研究[J].中国妇产科临床杂志,2014,15(6):512-514.
-
2周莹,谷元,张思瑶,高宇,张如月,尚海花,武丽南,司端运.银杏内酯滴丸在健康受试者体内的药动学研究[J].中草药,2020,51(9):2472-2480. 被引量：2
二级引证文献2
-
1邢宇,李雄,于颖.银杏内酯B脂质体的处方与制备工艺研究[J].中国现代应用药学,2021,38(6):697-703. 被引量：11
-
2段黎娟,黄小强,贾安,王丽,黄涛.薯蓣皂苷元滴丸制备工艺优化及其体内药动学研究[J].中成药,2024,46(3):947-951.
-
1曾跃华,陈云龙.葛根素治疗冠心病及对活化血小板的影响[J].长春中医药大学学报,2011,27(6):997-997. 被引量：7
-
2李洪亮,熊辉,陈永刚,乔静.高效液相色谱法测定人血清中5-羟色胺含量[J].山西医药杂志（下半月）,2009,38(10):876-877. 被引量：2
-
3万颖,屈晓雯,全胜麟.参芪扶正注射液对冠心病患者活化血小板的影响[J].中国临床医生杂志,2005,33(8):45-46. 被引量：2
-
4万颖,吴敏,师红林,董昆芸.络泰注射液对冠心病病人活化血小板的影响[J].中西医结合心脑血管病杂志,2006,4(9):806-806.
-
5王宁,顾锡镇,邓颖,袁昌文.疏血通注射液对急性脑梗死患者血小板活化的影响[J].南京中医药大学学报,2004,20(3):178-179. 被引量：16
-
6刘伟,李红.银杏叶提取物的药理作用及其在眼科疾病的临床研究进展[J].国际眼科杂志,2008,8(8):1647-1649. 被引量：4
-
7朱贤关,李忠东,王建昌,孟如松.银杏叶提取物对活化血小板刺激人冠状动脉内皮细胞产生ROS以及表达LOX-1和磷酸化p38MAPK的影响[J].中国老年学杂志,2012,32(3):546-548. 被引量：8
-
8马玉琛,周蕾,陈冬志,高伟敏,王玉乾,李春晓,孟明.蛭元方对血小板加剧的类风湿关节炎滑膜炎症和增生的影响[J].中国实验方剂学杂志,2012,18(18):182-186.
-
9徐士欣,张军平,李伟,仲爱芹.活化血小板释放产物对内皮细胞的损伤及丹酚酸B的保护效应[J].中华老年心脑血管病杂志,2012,14(2):183-185.
-
10冯纬纭.培土生金法治疗常年性变应性鼻炎的临床研究[J].广西中医药,2010,33(5):8-10. 被引量：1
