摘要
目的:观察乌司他丁在急性肺损伤/急性呼吸窘迫综合征中的治疗效果。方法:将52例急性肺损伤/急性呼吸窘迫综合征患者随机分为对照组(26例)和治疗组(26例),对照组予常规综合治疗,治疗组在此基础上加用乌司他丁辅助治疗。比较两组呼吸、心率、平均动脉压、血气分析结果及死亡率。结果:治疗组治疗后呼吸频率、心率、氧分压、动脉血氧饱和度分别为(18.9±3.6)次/min、(78.3±9.5)次/min、(98.4±10.5)mm Hg、(96.9±3.1)%,效果优于对照组的(21.3±3.2)次/min、(86.5±10.7)次/min、(75.9±8.7)mm Hg、(79.2±5.9)%,差异有统计学意义(P<0.05);对照组死亡率为26.9%(7/26),治疗组死亡率为11.5%(3/26),两组比较差异有统计学意义(P<0.05)。结论:乌司他丁辅助治疗急性肺损伤/急性呼吸窘迫综合征疗效确切,可推广应用。
Objective： To observe the efficacy of Ulinastain to the acute lunginjury/acute respiratory distress syndrome.Methods： 52 cases of patients with acute lunginjury/acute respiratory distress syndrome were randomly divided into control group（26 cases） and treatment group（26 cases）.The control group was treated by routine combined therapy,and the treatment group was treated by Ulinastain for injection based on the routine combined therapy.And then the respiratory rate,heart rate,mean arterial pressure and blood-gas analysis,mortality rate of the two groups were compared.Results： The respiratory rate,heart rate,PaO2,SaO2 of the treatment group was（18.9±3.6） times/min,（78.3±9.5） times/min,（98.4±10.5） mm Hg,（96.9±3.1）% respectively,all were superior to the（21.3±3.2） times /min,（86.5±10.7） times /min,（75.9±8.7） mm Hg,（79.2±5.9）% of the control group,the differences were significant（P0.05）;the mortality rate of the control group was 26.9%（7/26）,which was higher than the 11.5%（3/26） of the treatment group,the difference was statistically significant（P0.05）.Conclusion： The efficacy of Ulinastain to the acute lunginjury/acute respiratory distress syndrome is exact,and it is worth of popularizing.
出处
《中国医药导报》
CAS
2011年第29期71-72,共2页
China Medical Herald
关键词
急性肺损伤/急性呼吸窘迫综合征
乌司他丁
血气分析
死亡率
Acute lunginjury/acute respiratory distress syndrome
Ulinastain
Blood-gas analysis
Mortality rate
