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BNP判断心力衰竭严重程度及其预后的价值 被引量:16

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摘要 目的探讨血浆脑钠肽(BNP)水平在心力衰竭严重性及预后评估中的临床价值。方法比较充血性心力衰竭患者112例及健康体检者30例血浆BNP浓度、心脏超声参数,并观察心衰各组住院期间和出院后6个月内不良心脏事件发生率及死亡率。结果各级别心功能组BNP水平明显高于对照组(P<0.01),随着心衰程度的加重,BNP水平逐渐升高,左室舒张末期内径增大,左室射血分数降低。血BNP水平与左室舒张末期内径呈显著正相关(r=0.712),与左室射血分数呈负相关(P=-0.703)。发生心脏事件者入院时血BNP水平明显高于未发生心脏事件者(P<0.01);住院期间4例死亡患者临终前24h内血浆BNP水平较入院时明显升高(P<0.01)。结论充血性心力衰竭患者血BNP水平越高,提示心力衰竭程度越严重,患者近期预后越差。经治疗BNP持续增高的患者可能系高危人群,值得警惕。
出处 《海南医学》 CAS 2011年第20期27-28,共2页 Hainan Medical Journal
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  • 1刘哲,宋晓东,惠汝太.B型钠尿肽最新研究进展[J].心血管病学进展,2009,30(1):89-92. 被引量:36
  • 2Law Y, Kell B, Feingold B, et al. Usefulness of plasma B-type natriuretic peptide to identify ventricular dysfunction in pediatric and adult patients with congenital heart diease[J]. Am J Cardio, 2005,95: 474-478.
  • 3Doust JA, Pietrzak E, Dobson A, et al. How well does B-type natriuretic peptide predict death and Cardiac events in patients with heart failure: systematic review[J]. Br Med J, 2005, 330: 625-633.
  • 4Alans S, Peter A. Cardiac natriuretic peptides : A proten window to cardiac function and clinical management[J]. J Rev cardio-vasc Med, 2003, 4(suppl4): 3-12.

二级参考文献24

  • 1朱红俊,龚少愚,邹逊,魏慧渊,陆曙.心力衰竭病因对血浆BNP水平的影响[J].临床荟萃,2007,22(1):27-28. 被引量:25
  • 2Felker GM, Petersen JW, Mark DB. Natriuretic peptides in the diagnosis and management of heart failure [ J ]. CMAJ,2006,175:611-617.
  • 3See R ,de Lemos JA. Current status of risk stratification methods in acute coronary syndromes [ J ]. Curr Cardiol Rep,2006,8 : 282-288.
  • 4Jaffe AS, Babuin L, Apple FS. Biomarkers in acute cardiac disease:the present and the future [J]. J Am Coll Cardiol,2006,48:1-11.
  • 5Kerr A J, Raffel OC, Whalley GA, et al. Elevated B-type natriuretic peptide despite normal left ventricular function on rest and exercise stress echocardiography in mitral regurgitation [ J]. Eur Heart J,2008,29( 3 ) :363-370.
  • 6Takahashi N, Yamamoto A, Tezuka S, et al. Assessment of left ventricular dyssynchrony during development of heart failure by a novel program using ECG-gated myocardial perfusion SPECT [ J ]. Circ J,2008.72( 3 ) :370-377.
  • 7Sakuragi S, Maruo T, Taniguchi M, et al. Radial augmentation index associated with increase in B-type natriuretic peptide in patients with hypertension [J] . Int J Cardiol,2008,130(3) :414-419.
  • 8Kaski JP,Tome-Esteban MT,Mead-Regan SJ ,et al. B-type natriuretic peptide predicts disease severity in children with hypertrophic cardiomyopathy [ J]. Heart ,2008,94(10) :1307-1311.
  • 9Suhr OB ,Anan I ,Backman C ,et al. Do troponin and B-natriuretic peptide detect cardiomyopathy in transthyretin amyloidosis [ J ] ? J Intern Med ,2008,263 (3) : 294-301.
  • 10Tsutamoto T,Sakai H ,Nishiyama K,et al. Direct comparison of transcardiac increase in brain natriuretic peptide (BNP) and N-terminal proBNP and prognosis in patients with chronic heart failure [ J ]. Circ J ,2007,71 (12) :1873-1878.

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