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载脂蛋白E4水平与阿尔采默病关系的分析 被引量:1

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摘要 载脂蛋白E(Apolipoprotein E,ApoE)为一种多形态载脂蛋白.表现三种主要异构型:ApoE2,E3,E4。它们在单一基因位点上分别有三种等位基因82,83及84编码。这三种异构型的不同组合构成六种不同表型(3种纯合子-E狐2,E3/E3,E4/E4和三种杂合子-E2/E3,E3/E4,E2/E4)。
作者 许瑚
出处 《中国现代医药杂志》 2011年第10期99-99,共1页 Modern Medicine Journal of China
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  • 1王袁,吴琪俊,施榕.糖尿病肾病与载脂蛋白E基因多态性相关性的Meta分析[J].上海交通大学学报(医学版),2011,31(5):625-631. 被引量:9
  • 2Donges B, Haupt LM, Lea RA, et al. Role of the apolipoprotein E and catechol - 0 - methyltransferase genes in prospective and ret- rospective memory traits [ J]. Gene, 2012, 506 (1): 135-140.
  • 3Hatters DM, Peters - Libeu CA, Weisgraber KH, et al. Apolipoprotein E structure insights into function [ J ]. Trend Biochem Sci, 2006, 31 (8): 445-454.
  • 4Grosskopf I, Shaish A, Afek A, et al. Apo- lipoprotein A - V modulates multiple atherogen- ic mechanisms in a mouse model of disturbed clearance of triglyceride - rich lipoproteins [J]. Atherosclerosis, 2012, 224 (1): 75 -83.
  • 5Hui DY, Basford JE. Distinct signaling mech- anisms for ApoE inhibition of cell migration and proliferation [ J ]. Neurobiol Aging 2005, 26 (3) : 317 -323.
  • 6Wang L, Wang W, Shah PK, et al. Dele- tion of tenascin - C gene exacerbates athero- sclerosis and induces intraplaque hemorrhage in Apo - E - deficient mice [ J]. Cardiovascular Pathology, 2012, 21 (5): 398-413.
  • 7Kolovou GD, Anagnostopoulou KK. Apoli- poprotein E polymorphism, age and coronary heart disease [ J]. Ageing Res Rev, 2007, 6 (2): 94-108.
  • 8Keavney B, Parish S, Palmer A, et al. Large - scale evidence that the cardiotoxicity of smoking is not significantly modified by the apolipoprotein E2/E3/FA genotype [ J ]. Lancet, 2003, 361 (9355): 396-398.
  • 9Guan J, Zhao HL, Baum L, et al. Apoli- poprotein E polymorphism and expression in type 2 diabetic patients with nephropathy: clinicopathological correlation [ J ]. Nephrol Dial Transplant, 2009, 24 ( 6 ) : 1889 - 1895.
  • 10Hsu CC, Kao WH, Coresh J, et al. Apoli- poprotein E and progression of chronic kidney disease [ J ]. JAMA, 2005, 293 (23): 2892 - 2899.

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