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术毕应用曲马多、芬太尼、舒芬太尼对脊柱内固定术苏醒和疼痛的影响

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摘要 目的比较术毕应用曲马多、芬太尼、舒芬太尼对脊柱内固定和融合术后苏醒和疼痛的影响。方法全麻下行脊柱内固定和融合术患者60例,随机均分为三组:曲马多组(Ⅰ组);芬太尼组(Ⅱ组);舒芬太尼组(Ⅲ组),手术结束前20min分别给予曲马多1mg/kg,芬太尼1.5μg/kg,舒芬太尼0.2μg/kg。记录术后患者呼吸恢复时间、睁眼时间、拔管时间;采用VAS评分评估患者苏醒期的镇痛情况,并观察镇痛期间不良反应情况。结果三组患者呼吸恢复时间、睁眼时间、拔管时间比较差异无显著性,无统计学意义。Ⅲ组苏醒期各时点的VAS评分分别为(0.9±0.4)分、(1.1±0.6)分、(1.3±0.8)分;Ⅱ组分别为(2.1±1.2)分、(3.1±1.4)分、(6.0±1.6)分;Ⅰ组分别为(5.7±1.4)分、(6.9±1.6)分、(8.1±1.4)分;m组苏醒期各时点的镇痛效果明显优于Ⅰ组、Ⅱ组(P〈0.05)。且Ⅲ组镇痛期间不良反应与I组、Ⅱ组比较无明显差异。结论术毕应用舒芬太尼对脊柱内固定和融合术术后苏醒快,疼痛轻,镇痛时间长,不良反应轻。
出处 《国际医药卫生导报》 2011年第20期2533-2535,共3页 International Medicine and Health Guidance News
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参考文献4

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