摘要
目的分析浙江省舟山地区妊娠合并梅毒及围生儿梅毒感染情况,为有效阻断母婴垂直传播提供依据。方法回顾性分析舟山市妇幼保健院2008-2009年分娩的6366例孕产妇梅毒检测结果和梅毒感染孕产妇所生新生儿结局与随访情况。结果 6366例孕产妇梅毒感染46例,感染率为0.72%,均为隐性梅毒;设梅毒感染孕产妇46例为感染组,6320例未感染孕产妇为对照组。妊娠梅毒感染孕产妇选择剖宫产的比例高,与对照组比较差异有统计学意义(P<0.05);在孕期对梅毒感染进行治疗的孕产妇,其新生儿梅毒筛查阳性的比例低(P<0.05);对梅毒感染孕产妇所生新生儿进行预防性抗梅毒治疗,经随访其梅毒检测结果均为阴性。结论利用婚检和孕前保健服务平台加大宣传力度,加强孕产妇早期检测及时发现梅毒感染者并对其进行规范治疗,可以降低先天梅毒婴儿发生。
Objective To analyze the syphilis infection status in pregnant women and their infants in Zhoushan,provide scientific evidence for blocking vertical transmission of syphilis.Methods The test results of 6366 pregnant women who gave birth in our hospital from 2008 to 2009,the outcomes and follow-up data of the infants were analyzed retrospectively.Results Forty six of 6366 pregnant women were positive for syphilis（0.72%）.All of them were infected with latent syphilis.The 46 pregnant women were regarded as infection group,the remaining were as control group.Pregnancy syphilis was the major reason to choose cesarean section among these pregnant women,the difference was significant between infection group and control group（P0.05）.The infection rate was low in the infants whose mothers received treatment during pregnancy（P0.05）.The preventive treatment was conducted for the infants of syphilis infected women,so the follow up results indicated they were all negative for syphilis.Conclusion Congenital syphilis can be well controlled by strengthening pre-marriage examination and the health care before pregnancy as well as the surveillance and standard treatment of syphilis in pregnancy.
出处
《疾病监测》
CAS
2011年第9期714-715,742,共3页
Disease Surveillance
基金
浙江省医药卫生科学研究基金(2010 SSA013)~~
关键词
妊娠合并梅毒
先天梅毒
围生儿结局
随访
syphilis during pregnancy
congenital syphilis
perinatal outcome
follow-up
