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人体上呼吸道口喉呼吸流涡结构演化对病毒气溶胶扩散的影响研究 被引量:2

Influence of Vortex Evolution in Human Mouth and Throat to the Diffusion of Virus Aerosol
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摘要 揭示涡结构演化对病毒气溶胶扩散的影响作用,对于有效防治呼吸道疾病具有非常重要的意义.本文运用大涡模拟的方法,对人体在循环呼吸模式下口喉模型内的涡结构演化及气溶胶扩散进行了数值仿真研究,分析了口喉模型内涡结构演化过程以及气溶胶扩散状态.结果表明:受呼吸流涡结构演化的影响,颗粒轨迹主要分布在上气道内涡量集中的区域;受横向涡结构和纵向涡结构的共同影响,部分病毒气溶胶颗粒具备了混合有环状轨迹和波状轨迹的螺旋状轨迹.本研究从微观角度揭示了涡结构演化与气溶胶扩散行为的关系,为深入认识病毒气溶胶上呼吸道传播特点提供了新的途径. Revealing the influential action of vortex evolution in human upper respiratory tract on diffusion of virus aerosol has great significance for the prevention and treatment of respiratory tract diseases.Large eddy simulation was used to simulate the vortex structure and the diffusion of virus aerosol in human mouth-throat model in cyclic respiratory pattern,and the vortex evolution in mouth-throat model with the trajectories of aerosol particles was discussed in this paper.The results show that the trajectories of virus aerosol particles congregate in regions with higher airflow vorticity affected by the vortex evolution in mouth-throat model.Due to the joint influence of transverse and longitudinal vortex,the helicoidal trajectories combined annular and wavy trajectories of aerosol particles appear in the model.This study disclosed the relationship between the vortex evolution and the diffusion of aerosol in human mouth and throat from the microcosmic angle,which provides a new way for deepening understanding of the propagating characteristics of virus aerosol in human upper respiratory tract.
出处 《中国科学:生命科学》 CSCD 北大核心 2011年第10期1000-1007,共8页 Scientia Sinica(Vitae)
基金 国家自然科学基金资助项目(批准号:31070832)
关键词 上呼吸道 口喉模型 呼吸流 涡结构演化 病毒气溶胶扩散 upper respiratory tract mouth-throat model breathing flow vortex evolution diffusion of virus aerosol
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  • 1Calay RK, Kurujareon Jutarat, Holde Arne Erik. Numerical simulation of respiratory flow patterns within human lung. Respiratory Physiology & Neurobiology, 2002, 130(2): 201-221.
  • 2Jayaraju ST, Brouns M, Verbanck S, et al. Fluid flow and particle deposition analysis in a realistic extrathoracic airway model using unstrrctured grids. Aerosol Science, 2007, 38(5): 625-644.
  • 3Zhang Z, Kleinstreuer C, Kim CS. Micro-particle transport and deposition in a human oral airway model. Aerosol Science, 2002, 33(12): 1635-1652.
  • 4Zhang Z, Kleinstreuer C. Cycle micron-size particle inhalation and deposition in a triple bifurcation lung airway model. Aerosol Science, 2002, 33(2): 257-281.
  • 5Liu Y, So RMC, Zhang HC. Modeling the bifurcating flow in an asymmetric human lung airway. Journal of Biomechanics, 2003(7): 951-959.
  • 6Zheng L, Kleinstreuer C, Zhang Z. Particle deposition in the human tracheobronchial airways due to transient in- spiratory flow patterns. Aerosol Science, 2007, 38(6): 625-644.
  • 7Renotte Christine, Bouffioux Vincent, Wilquem FreHderic. Numerical 3D analysis of oscillatory flow in the time- varying laryngeal channel. Journal of Biomechanics, 2000, 33(12): 1637-1644.
  • 8Zhang Z, Kleinstreuer C. Species heat and mass transfer in a human upper airway model. International Journal of Heat and Mass Transfer, 2003, 46(25): 4755-4768.
  • 9Zhang Z, Kleinstreuer C, Donohue JF, et al. Comparison of micro- and nano-size particle depositions in a human upper airway model. Aerosol Science, 2005, 36(2): 211-233.
  • 10Zhang Z, Kleinstreuer C. Airflow structures and nanoparticle deposition in a human upper airway model. Compututional Physics, 2004, 198(1): 178-210.

共引文献19

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  • 1向屏,郭印诚.具有壁面射流激励的圆管内气相流动大涡模拟[J].计算力学学报,2006,23(1):87-92. 被引量:5
  • 2Martin A N,John E C. Large eddy simulation of high frequency oscillating flow in an asymmetric branching airway model [J]. Medical Engineering Physics, 2009,31(9) : 1148-1153.
  • 3Kleinstreuer C, Zhang Z. Airflow and particle trans- port in the human respiratory system [J]. AnnualRe- view of Fluid Mechanics, 2010,42 : 301-334.
  • 4Nazridoust K, Asgharian B. Unsteady-state airflow and particle deposition in a three-generation human lung geometry [J]. Inhalation Toxicology, 2008, 20(6) :595-610.
  • 5Choi L T, Tu J Y, Li H F, et al. Flow and particle deposition patterns in a realistic human double bifur- cation airway model [J ]. Inhalation Toxicology, 2007,19(2) : 117-131.
  • 6Hunt J C, Wray A A, Moin P. Eddies streams and convergence zones in turbulent flows [A]. Procee- dings of the Summer Program,Center for Turbulence Research[C]. California: Stanford University, 1988.
  • 7Wolfgang A,Wall T R. Fluid-structure interaction in lower airways of CT-based lung geometries [J]. International Journal for Numerical Methods in Fluids, 2008,57 : 653-675.
  • 8徐新喜,赵秀国,刘亚军.循环吸气支气管内瞬态气流运动特性的仿真研究[J].中国生物医学工程学报,2008,27(6):887-893. 被引量:3
  • 9徐新喜,赵秀国,谭树林,刘亚军,高振海.循环呼吸模式口喉模型内气流运动特性数值模拟[J].力学学报,2010,42(2):183-190. 被引量:12
  • 10徐新喜,赵秀国,谭树林,刘亚军,高振海.人体上呼吸道内气流运动特性的数值模拟分析[J].计算力学学报,2010,27(5):881-886. 被引量:15

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