摘要
干细胞移植可改善心脏功能,其机制可能为移植的细胞分化为心肌细胞,促进宿主细胞分泌促进血管生成的细胞因子及改善宿主心脏局部结构,提高局部心肌弹力,参与宿主心脏收缩。回顾近年相关权威研究,基础临床研究均证实干细胞移植治疗扩张型心肌病合并心力衰竭是一项安全有效的干预措施。
Stem cell transplantation improves heart function of aceeptor,the mechanism of which maybe lies in the differentiation of transplanted cells into cardiomyocytes, stimulation of the cell secretion and angiogenesis factors, improvement of local heart structure and increase in the heart elasticity and participation in systole. Our review on recent authoritative studies had demonstrated that stem cell transplantation is a safe and effective way for treating dilated cardiomyopathy complicated with heart failure.
出处
《中国实用内科杂志》
CAS
CSCD
北大核心
2011年第10期753-755,共3页
Chinese Journal of Practical Internal Medicine
关键词
扩张型心肌病
干细胞移植
心力衰竭
dilated cardiomyopathy
stem cell transplantation
heart failure
