摘要
目的研究沙利度胺对Graves病患者甲状腺功能的影响。方法选择2006年8月至2009年3月宁波市第二医院内分泌科收治的Graves病患者18例,随机分为抗甲状腺药物单药组10例(单药组)及沙利度胺与抗甲状腺药联合组(联合组)8例。比较治疗前及治疗3、6周后患者甲状腺功能。结果沙利度胺联合组与单药组相比,所需抗甲状腺药物剂量明显减少。结论沙利度胺与抗甲状腺药物合用时,影响Graves病患者甲状腺功能。
Objective To evaluate the impact of thalidomide on thyroid function in patients with Graves＇ disease, Methods A total of 18 patients with Graves＇ disease were divided into group A （on antithyroid agent, n = 10） and group B （on thalidomid and antithyroid agent, n = 10）. The function of thyroid gland was examined before and at weeks 3 and 6 after treatment. Results Lower dose of antithyroid agent was needed for patients on combined therapy with thalidomid than those on antithyroid agent alone. Conclusion Thalidomide may affect the thyroid function in patients with Graves＇ disease treated with antithyroid agent.
出处
《中国实用内科杂志》
CAS
CSCD
北大核心
2011年第10期819-820,共2页
Chinese Journal of Practical Internal Medicine
