成体血管新生与细胞自主调节血管特异性microRNAs

Postnatal neovasculation and cell-autonomous angiomiRs

下载PDF

导出

摘要成体血管新生在整形美容外科有着广泛的应用前景,各种皮片、皮瓣以及脂肪移植等,都需要尽快形成新生血管供应移植组织的血运。多年来众多学者从各种生长因子到干细胞,对促进成体血管新生做了大量的研究,但其有效性和安全性局限。如何有效调节成体血管新生,

作者曾淑红易成刚郭树忠

机构地区第四军医大学西京医院整形外科

出处《中国美容医学》 CAS 2011年第10期1652-1654,共3页 Chinese Journal of Aesthetic Medicine

关键词 MICRORNAS 血管新生调节血管干细胞成体特异性整形美容外科脂肪移植

参考文献28

1Carmeliet P.Angiogenesis in health and disease[J].Nat Med,2003,9(6):653-660.
2Pugh CW,Ratcliffe PJ.Regulation of angiogeneis by hypoxia:role of the HIF system[J].Nat Med,2003,9(6):677-684.
3Annette S,Klara B,Wilhelm B.Endothelial Precursor Cell Migration During Vasculogenesis[J].Circ Res,2007,101 (2):125-136.
4Tongers J,Roncalli JG,Losordo DW.Role of endothelial progenitor cells during ischemia-induced vasculogenesis and collateral formation[J].Microvasc Res,2010,79(3):200-206.
5Melany C.Insight into mechanisms behind arteriogenesis:what does the future hold?[J].Leukoc Biol,2008,84(6):1379-1391.
6Shusheng Wang,Eric NOlson.AngiomiRs-Key regulators of angiogenesis[J].Curr Opin Genet Dev,2009,19(3):205-211.
7Kuehbacher A,Urbich C,Zeiher AM,et al.Role of Dicer and Drosha for endothelial microRNA expression and angiogenesis[J].Circ Res,2007,101(1):59-68.
8Suarez Y,Fernandez-Hemando C,Pober JS,et al.Dicer dependent microRNAs regulate gene expression and functions in human endothelial cells[J].Circ Res,2007,100(8):1164-1173.
9Fish JE,Santoro MM,Morton SU,et al.miR-126 regulates angiogenic signaling and vascular integrity[J].Dev Ce11,2008,15(2):272-284.
10Wang S,Aurora AB,Johnson BA,et al.The endothelial specific microRNA miR-126 governs vascular integrity and angiogenesis[J].Dev Ce11,2008,15(2):261-271.

中国美容医学

2011年第10期

内容加载中请稍等...