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糖皮质激素性骨质疏松预防和治疗新进展 被引量:5

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摘要 糖皮质激素(glucocorticoid,GC)由于其强大的抗炎和免疫抑制作用而被广泛应用于多种疾病,然而GC可致多种不良反应,如胰岛素抵抗、高血压、青光眼和骨质疏松症。GC诱导的骨质疏松症(glueoeorticoid induced osteoporosis,GIOP)被认为是一种最严重的灾难性不良反应.
作者 赵东宝
出处 《内科理论与实践》 2011年第5期348-351,共4页 Journal of Internal Medicine Concepts & Practice
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参考文献5

  • 1Reid DM,Devogelaer JP,Saag K,et al.Zoledronic acid and risedronate in the prevention and treatment of glucocorticoid-induced osteoporosis (HORIZON):a multicentre,double-blind,double-dummy,randomised controlled trial[J].Lancet,2009,373(9671):1253-1263.
  • 2van Staa TP,Geusens P,Pols HA,et al.A simple score for estimating the long-term risk of fracture in patients using oral glucocorticoids[J].QJM,2005,98(3):191-198.
  • 3American College of Rheumatology Ad Hoc Committee on Glucocorticoid-Induced Osteoporosis.Recommendations for the prevention and treatment of glucocorticoid-induced osteoporosis:2001 update[J].Arthritis Rheum,2001,44(7):1496-1503.
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  • 5Saag KG,Zanchetta JR,Devogelaer JP,et al.Effects of teriparatide versus alendronate for treating glucocorticoid-induced osteoporosis:thirty-six-month results of a randomized,double-blind,controlled trial[J].Arthritis Rheum,2009,60(11):3346-3355.

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