摘要
目的观察翼状胬肉切除联合自体角膜缘干细胞移植术的临床疗效。方法选取2008年1月-2010年12月期间长沙市中心医院收治的39例(46眼)翼状胬肉患者,随机分为翼状胬肉单纯切除术组(对照组)及翼状胬肉切除联合自体角膜缘干细胞移植术组(治疗组),比较其疗效。结果对照组患者复发率为13.6%,上皮修复时间为(5.81±0.84)d;而治疗组复发率仅为4.35%,上皮修复时间为(3.03±0.79)d。两者相比,差异有统计学意义(P<0.05)。结论翼状胬肉切除联合自体角膜缘干细胞移植术与翼状胬肉单纯切除术相比,可以有效地降低复发率,缩短角膜上皮修复时间,为治疗翼状胬肉较为理想有效的方法。
Objective To observe the clinical therapeutic effect of pterygium excision combined with autologous limbal stem cell transplantation. Methods Thirty-nine cases（46 eyes） hospitalized in Changsha Central Hospital from January 2008 to December 2010 were randomly divided into pterygium excision alone group（control group） and pterygium excision combined with autologous limbal stem cell transplantation group（treatment group）,and the therapeutic efficacy was compared between the two groups. Results The recurrence rates of control group and treatment group were 13.6% and 4.35%,respectively.The epithelial repair time was（5.81±0.84） d in control group and（3.03±0.79） d in treatment group.There were statistically significant differences between the two groups（P〈0.05）. Conclusions Compared with pterygium excision alone,the surgery of pterygium excision combined with autologous limbal stem cell transplantation can effectively reduce the recurrence rate and shorten the time of corneal epithelial repair.It is an ideal and effective method for the treatment of pterygium.
出处
《实用预防医学》
CAS
2011年第10期1950-1951,共2页
Practical Preventive Medicine
关键词
自体角膜缘干细胞移植术
单纯切除
翼状胬肉
疗效
Autologous limbal stem cell transplantation
Simple excision
Pterygium
Therapeutic effect
