摘要
目的:探讨HIV患者HCMV DNA与CD4+T细胞计数和机会性感染的相关性。方法:对262例HIV患者外周血联合检测HCMV DNA与CD4+T细胞计数,并对其病程作回顾分析。结果:262例HIV阳性患者中HCMV DNA阳性44例(占16.8%),其中HCMV DNA阳性组CD4百分含量为4.43±5.41%,CD4绝对计数为26.73±46.74个/μl明显低于阴性组(P<0.001),HCMV感染的患者发生各种机会性感染和肿瘤的机会明显高于HCMV阴性组,HIV和HCMV双重感染的患者CD4+T细胞绝对值小于200个/μl有43例(占97.7%)。结论:HIV和HCMV双重感染的患者处于AIDS发病阶段,HCMV DNA与CD4+T细胞数量和机会性感染有相关性。
Objective：To evaluate the correlation of HCMV DNA and the CD4^＋T cell count and opportunistic infections in HIV-infected patients.Methods： 262 cases of HIV-infected patients were tested for HCMV DNA and the CD4^＋T cell count in peripheral blood,and the course of disease was retrospectively analyzed.Results： HCMV DNA was positive in 44 of 262（16.8%） HIV-infected patients.The percentage of CD4^＋T cell in HCMV-positive group was 4.43±5.41 %and CD4^＋T cell absolute counts in HCMV-positive group were 26.73±46.74 cells/μl,which was significantly lower than the HCMV-negative group of HIV-infected patients（P0.001）,but with higher incidences of opportunistic infections and tumors.HIV and HCMV double-infected patients with CD4^＋T cell absolute value 200/μl were 43 cases（97.7%）.Conclusion： HIV and HCMV double-infected patients are in the AIDS disease onset stage,and HCMV DNA are related with the quantities of CD4^＋T cells and opportunistic infections.
出处
《中国卫生检验杂志》
CAS
2011年第10期2485-2486,2495,共3页
Chinese Journal of Health Laboratory Technology
