摘要
对羟亚胺苯丙酸乙酯换还原制备苯丙氨酸进行了研究,考察了催化剂、温度、溶剂、还原剂用量对该反应性能的影响,研究结果为：向体系中加入少量的纳非晶态镍,可以高效率地完成还原,收率〉85%,以甲醇-水为溶剂时收率较优。
The reaction of benzene pyruvic acid oximide ethyl reduce to phentermine was studied.The effects of reaction temperature,catalyst,solvent,reductant on the yield were investigated.The optimum conditions were obtained as followed： when adding some amorphous into reaction system,and solvent was methanol-water,the yield of catalytic reduction reaction was higher than 85%.
出处
《化工技术与开发》
CAS
2011年第10期19-21,共3页
Technology & Development of Chemical Industry
关键词
羟亚胺苯丙酸乙酯
苯丙氨酸
还原催化
benzene pyruvic acid oximide ethyl
phentermine
catalytic reduction
