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依达拉奉联合羟乙基淀粉治疗急性脑分水岭梗死临床疗效观察 被引量:2

Clinical Efficacy of Edaravone Combined with Hydroxyethyl Starch in Treatment of Acute Cerebral Watershed Infarction
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摘要 目的:观察依达拉奉联合羟乙基淀粉治疗脑分水岭梗死临床疗效。方法:将86例急性脑分水岭梗死的患者随机分为治疗组44例和对照组42例,对照组常规活血,抗血小板聚集药物同时予羟乙基淀粉500ml静点治疗,治疗组在对照组基础上加用依达拉奉治疗,治疗前及治疗10天行神经功能缺损程度评分并判断疗效。结果:治疗10天后两组患者神经功能缺损评分较治疗前均有好转(P<0.01),治疗组神经功能缺损评分明显低于对照组(p<0.01);治疗组患者神经功能缺损评分减少值明显高于对照组(P<0.01)。两组患者均未出现明显不良反应。结论:依达拉奉联合羟乙基淀粉治疗急性脑分水岭梗死临床疗效安全有效。 Objective:To assess the effects of edarasone combined with hydroxyethyl starch on acute cerebral watershed infarction.Methods: 86 patents with acutc cerebral watershed infaretion were nmdomly divided into trcatment group of 44 patients and the control group, 42 palients in the conlrol group of normal blood enculation,anti-platelet aggregation drugs while 1 500ml intravenous hydroxyethyl starch treatment,the trcatment group were based on the use of edatavone treatment,before treatment and 10 days of nerve function dcficit score and to determine efficacy.Results:10 days after the tow groups of patients with neurological deficit scores were better tha before treatment(P〈0.01),treatment group.neurological deficit score was significantly lower than the control group (P〈0.01);patients treated with reduced ncurological deficit scores valac was signigicantly higher (P〈0.01).Two groups of patients were no obvious adverse reactions.Conclusion:The combined hydroxycthyl starch edarvone treatment of acute cerebral watershed infarction safe and effective clinical trcatmetn.
出处 《中国医药导刊》 2011年第8期1358-1359,共2页 Chinese Journal of Medicinal Guide
关键词 依达拉奉 羟乙基淀粉 急性脑分水岭梗死 Edaravone Hydroxyethylstarch Acute cercbrai watershed infarction
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