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环孢素联合雄激素及复方皂矾丸治疗再生障碍性贫血疗效分析 被引量：4

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摘要 目的探讨环孢素联合雄激素及复方皂矾丸治疗再生障碍性贫血的疗效。方法治疗组服用环孢素100mg,2次/d,同时加用雄激素及复方皂矾丸;对照组应用雄激素及复方皂矾丸,用量及方法同治疗组,但不服用环孢素。结果治疗组59例,基本治愈2例,缓解25例,明显进步27例,无效5例,总有效率91.53%;对照组53例,基本治愈1例,缓解12例,明显进步21例,无效19例,总有效率64.15%。两组比较差异有统计学意义(P<0.05)。结论环孢素联合雄激素及复方皂矾丸治疗再生障碍性贫血疗效较好,未增加明显不良反应。
作者 王雪宝
机构地区 吉林省肿瘤医院药剂科
出处 《中国误诊学杂志》 CAS 2011年第30期7396-7397,共2页 Chinese Journal of Misdiagnostics
关键词 贫血 再生障碍性/中西医结合疗法 皂矾/治疗应用 环孢菌素/治疗应用 雄激素类/治疗应用
分类号 R556.505.8 [医药卫生—血液循环系统疾病]
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  • 1Hamerschlak N, Maluf E, Pasquini R, et al. Incidence of aplastic anemia and agranulocytosis in Latin America-the LATIN study. Sao Paulo Med J,2005,123 : 101-104.
  • 2McCahon E, Tang K, Rogers PC, et al. The impact of Asian descent on the incidence of acquired severe aplastic anaemia in children. Br J Haematol,2003 ,121:170-172.
  • 3Saunthararajah Y, Nakamura R, Nam JM, et al. HLA-DR15 (DR2) is overrepresented in myelodysplastic syndrome and aplastic anemia and predicts a response to immunosuppression in myelodysplastic syndrome. Blood,2002,100 : 1570-1574.
  • 4Maciejewski JP, Follmann D, Nakamura R, et al. Increased frequency of HLA-DR2 in patients with paroxysmal nocturnal hemoglobinuria and the PNH/aplastic anemia syndrome. Blood,2001, 98:3513-3519.
  • 5Sugimori C, Yamazaki H. Roles of DRB1 * 1501 and DRB1 * 1502 in the pathogenesis of aplastic anemia. Exp Hematol,2007, 35 : 13-20.
  • 6Kapustin SI, Popova TI, Lyshchov AA, et al. HLA-DR4-Ala74 beta is associated with risk and poor outcome of severe aplastic anemia. Ann Hematol,2001,80 : 66-71.
  • 7Fuhrer M, Dumer J, Brynnler G, et al. HLA association is different in children and adults with severe acquired aplastic anemia. Pediatr Blood Cancer,2007,48: 186-191.
  • 8Gidvani V, Ramkissoon S, Sloand EM, et al. Cytokine gene polymorphisms in acquired bone marrow failure. Am J Hematol,2007, 82:721-724.
  • 9Dufour C, Capasso M, Svahn J, et al. Homozygosis for (12) CA repeats in the first intron of the human IFN-gamma gene is significandy associated with the risk of aplastic anaemia in Caucasian population. Br J Haematol,2004 ,126 :682-685.
  • 10Svahn J, Capasso M, Lanciotti M, et al. The polymorphisms - 318C→T in the promoter and 49A→G in exon 1 of CTLA4 and the risk of aplastic anemia in a Caucasian population. Bone Marrow Transplant,2005,35 Suppl:S89-92.

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中国误诊学杂志
2011年 第30期

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