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新生儿胆道闭锁与病毒感染相关性的研究进展 被引量:2

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摘要 新生儿胆道闭锁(biliary atresia,BA)是一种新生儿出生时或出生后几周内出现肝内胆管、肝管或胆总管发生闭锁或不发育的胆道破坏性疾病。该病在我国和日本的发病率要高于欧美地区,其临床表现为不同程度的持续性黄疸、陶土色粪便、浓茶样尿和肝脾肿大,晚期会出现胆汁性肝硬化、腹水、腹壁静脉曲张和凝血障碍,绝大多数患儿最终需进行肝移植手术,如不进行有效治疗,最终可因肝硬化、肝衰竭或严重的血凝障碍而导致死亡。
作者 李凡 钱渊
出处 《国际病毒学杂志》 2011年第5期160-162,共3页 International Journal of Virology
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