摘要
黑色素瘤抗原A(MAGE—A)是一组肿瘤相关性抗原,主要表达于以黑色素瘤为主的多种恶性肿瘤组织中。肝细胞癌(HCC)是发生于肝脏的上皮性恶性肿瘤,患病率高,寻找有效的诊断和治疗方法成为极其迫切的任务。目前已证实MAGE.A基因在HCC组织中高表达,对HCC诊治及预后判断具有重要意义。
Melanoma antigen A is a kind of tumor-associated antigen, which expresses in various types of hunman malignant tumor tissues especially in melanoma. Hepatocellular carcinoma (HCC) is a kind of malignant epithelial tumor with high incidence which occurs in liver. Searching for effective diagnosis and treatment methods of it become a pressing task. It is confirmed that MAGE-A gene is highly expressed in HCC tissues which has great significance to the diagnosis, treatment and prognosis for HCC.
出处
《国际肿瘤学杂志》
CAS
2011年第10期783-786,共4页
Journal of International Oncology
关键词
黑色素瘤抗原
癌
肝细胞
免疫疗法
Melanoma antigens
Carcinoma, hepatocellular
Immunotherapy