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瑞芬太尼复合丙泊酚在支撑喉镜下喉显微外科手术中的应用观察 被引量:4

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摘要 目的探讨支撑喉镜下喉显微外科手术患者不同阶段血流动力学和机体对伤害性刺激应激反应的变化。方法拟行支撑喉镜下喉显微外科手术患者50例,年龄21~58岁,ASAⅠ或Ⅱ级,随机分为两组(n=25),丙泊酚复合芬太尼全麻组为对照组(F组),丙泊酚复合瑞芬太尼全麻组为观察组(R组)。分别于麻醉前(T_0)、置入支撑镜即刻(T_1)、置入支撑喉镜后1 min(T_2)和拔管后1 min(T_3)时监测SBP、MAP、HR,抽取肘静脉血,测定血浆中去甲肾上腺素(NE)和肾上腺素(E)的浓度。结果与T_0时比较,F组T_(1,2,3)时SBP、MAP、HR、血浆NE和E浓度升高(P<0.05);与R组比较,F组T_(1,2,3)时SBP、MAP、HR、血浆NE和E浓度升高(P<0.05)。结论支撑喉镜下喉显微外科手术患者不同阶段中,置入支撑喉镜阶段的伤害性刺激最强;瑞芬太尼复合丙泊酚麻醉维持术中血流动力学稳定,伤害性刺激应激反应小,可安全用于支撑喉镜喉显微外科手术。
出处 《中国医学创新》 CAS 2011年第31期39-40,共2页 Medical Innovation of China
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