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3,6-二氨基-N-异丁基邻苯二甲酰亚胺的合成 被引量:2

Synthesis of 3,6-Diamino-N-isobutyl Phthalimide
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摘要 以3-硝基邻苯二甲酸为原料,经脱水成酐、氨解、还原酰化、硝化、水解、还原等六步反应合成了一种新型的环芳酰胺的构筑单元对苯二胺衍生物——3,6-二氨基-N-异丁基邻苯二甲酰亚胺,总收率16.4%,其结构经1H NMR,13C NMR和ESI-MS表征。 A novel derivative of phenylene diamine,3,6-diamino-N-isobutyl phthalimide,was designed and synthesized by a six-step reaction of dehydration,ammonolysis,reduction and acylation,nitration,hydrolysis and hydrogenation from 3-nitrophthalic acid.The total yield was 16.4% and the structures were characterized by 1H NMR,13C NMR and ESI-MS.
出处 《合成化学》 CAS CSCD 北大核心 2011年第6期744-746,共3页 Chinese Journal of Synthetic Chemistry
关键词 3 6-二氨基-N-异丁基邻苯二甲酰亚胺 3-硝基邻苯二甲酸 对苯二胺衍生物 合成 3 6-diamino-N-isobutylphthalimide 3-nitrophthalic acid p-phenylene diamine derivative synthesis
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参考文献18

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  • 91c: ^1H NMR δ: 10.13(s, 1H), 10.00(s, 1H), 9.64 (s, 1H), 9.29(s, 1H), 8.98(s, 1H), 8.72(s, 1H), 8.63(dd, J= 1.5 Hz, 7.5 Hz, 1H ), 7.02 - 6.97(m, 2H), 6.87(dd, J=1.4 Hz, 7.6 Hz, 1H ), 6.52(s, 1H), 6.50(s, 1H), 6.18(s, 1H), 4.47(t, J=4.8 Hz, 2H), 4.28 -4.26(m, 4H), 4. 07(brs, 4H), 3.97-3.94(m, 2H), 3.92 -3.88(m, 11H), 3.77 -3.47(m, 30H), 3.44 -3.43(m, 4H), 3.33 (s, 3H), 3.30(s, 6H), 3.28(s, 3H).
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