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广西女性性工作者暴露前药物预防HIV感染接受意愿及其影响因素研究 被引量:4

Acceptability and influencing factors on pre-exposure prophylaxis programs among female sex workers
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摘要 目的了解广西地区南宁、柳州、北海市女性性工作者(Fsws)对暴露前药物预防(PrEP)HIv感染的接受意愿及其影响因素。方法采用横断面设计,方便抽样的方法选取3市405名FSWs进行问卷调查,了解FSWs的AIDS相关危险行为、对PrEP的知晓情况及其接受意愿。结果在了解PrEP后,对于“如果PrEP预防HIV感染安全、有效且免费提供”,405人中有85.9%表示愿意接受。logistic回归分析显示,与PrEP接受意愿有关的因素为:工作场所(OR=2.256,P=0.009)、月经济收入(OR=0.257,P=0.004)、与家人的关系(OR=0.338,P=0.012)、AIDS知晓情况(OR=2.802,P=0.028)、认为HIV感染危险来自陌生性伴(OR=o.363,P=0.049)、老板是否规定使用安全套(OR=0.432,P=0.010)、商业性行为时是否全程使用安全套(OR=3.010,P=0.002)、是否使用过药物预防性病(OR=3.570,P=0.049)。结论对HIV/AIDS相关知识的知晓程度及自我保护意识的高低可能是影响FSWs接受PrEP的主要因素。以健康教育的形式官侍PrEP旱提高其接蛋意愿的较好方式。 Objective To study the acceptability of pre-exposure prophylaxis (PREP) program on prevention of human immunodeficiency virus (HIV)infection among female sex workers (FSWs) in Guangxi of China. Methods A cross-sectional survey using convenience sampling was administered among 405 FSWs in Nanning, Liuzhou and Beihai cities of Guangxi, China. Self-designed questionnaire, face to face interviews were used to collect HIV-related risk behaviors, knowledge and acceptability of PREP. Results After an introduction on PREP, presuming that it was effective, safe and free of charge, 85.9% of the 405 FSWs said they would use it. Data from logistic regression analysis showed that significant factors of intent to use PrEP would include the followings: workplace (OR:2.256, P=0.009) , monthly income (OR=-0.257, P:0.004) , family closeness (OR=0.338, P=0.012) , knowledge on HIV/AIDS (OR=2.802, P=0.028) , HIV/AIDS risk was introduced from a strange client (OR=0.363, P=0.049), whether the gatekeeper ordering the use of condom (OR=0.432, P=0.010) , whether consistent using condom with clients (OR=3.010, P= 0.002), whether ever using drugs to prevent STD infection (OR=3.570, P=0.049) etc. Conclusion Awareness on HIV/AIDS knowledge and self-protection seemed the main influential factors while health education might promote the acceptability of PREP.
出处 《中华流行病学杂志》 CAS CSCD 北大核心 2011年第11期1091-1094,共4页 Chinese Journal of Epidemiology
基金 国家“十一五”科技重大专项(2008ZX10001-016) 广西高教人才小高地建设创新团队资助计划(桂教人[2010]38号) 广西“新世纪十百千人才工程”人选课题(桂人社办发[2010]319号)
关键词 艾滋病病毒 女性性工作者 暴露前药物预防 接受意愿 Human immunodeficiency virus Female sex workers Pre-exposure prophylaxis Acceptability
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同被引文献49

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