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依达拉奉治疗急性脑梗死的临床分析

The Clinical Analysis of Edaravone Treatment of Acute Cerebral Infarction
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摘要 目的探讨依达拉奉注射液治疗急性脑梗死的有效性及安全性。方法将80例急性脑梗死患者随机分为实验组40例及对照组40例,两组患者均给予常规治疗方法,实验组同时给予依达拉奉注射液治疗。治疗14d后观察两组患者治疗的日常生活能力评分(ADL)、有效率及药物的安全性。结果治疗组日常生活能力评分(ADL)和有效率明显高于对照组(P<0.05),两组治疗后安全性无统计学差异(P>0.05)。结论依达拉奉治疗急性脑梗死能明显改善神经功能障碍,提高日常生活自理能力,安全有效,值得临床推广。 Objective To observe the efficacy and safety of Edaravone for acute cerebral infarction. Methods Select 80 patients with acute cerebral infarction, were randomly divided into two groups, with 40 in the test group and 40 in the control group, the two groups were given routine therapy, the treatment group took edaravone on the basis of routine therapy.the activity of daily living(ADL) with Barthel Index(BI),the effective rates and safety were observed after 14 days. Results The test group of scores of BI、efficiency rate was significantly higher than the control group(P0.05), the two groups of safety has no significantly difference(P0.05) after the treatment. Conclusion Edaravone can improve symptoms of neurological functional disturbance, enhance daily life self-care ability, it is safe and effective, it has great value in clinical application.
机构地区 蕉岭县人民医院
出处 《中国医药指南》 2011年第30期234-235,共2页 Guide of China Medicine
关键词 急性脑梗死 依达拉奉 临床分析 Acute cerebral infarction Edaravone Clinical analysis
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  • 1Felberg RA,Burgin WS,Grotta JC.Neuroprotection and the ischemic cascade[J].CNS Spectrums,2000,5:52-58.
  • 2Li Y,Chopp M,Jiang N,et al.Temporal profile of in situ DNA fragmentation after transient middle cerebral artery occlusion in the rat[J].J Cereb Blood Flow Metab,1995,15(3):389-397.
  • 3Takamatsu Y,Yuki S,Watanabe T.Studies on the concentration of 3-methyl-1-phenyl-2-pyrazolin-5-one(MCI-186)in MCA occlusion and reperfusion model of rats[J].Jpn Pharmacol Ther,1997,25(Suppl):SI785-SI791.
  • 4Tanaka M.Pharmacological and clinical profile of the free radical scavenger edaravone as a neuroprotective agent[J].Nippon Yakurigaku Zasshi,2002,119(5):301-308.
  • 5Tatsushi K,Yasuo K.Mild hypothermia enhances efficacy of neuroprotective agents in cerebral ischemia in rats[J].International Congress Series,2003,1252:93-101.
  • 6Suda S;Igarashi H;Arai Y;et a.l Effect of edaravone,a free radical scavenger,on ischemic cerebral edema assessed bymagnetic resonance imaging[J],2007.
  • 7吴婷;王蔚;丁新生.依达拉奉对培养乳鼠海马神经元缺血再灌注损伤的保护作用[J]药学与l豳床研究,2007(05).
  • 8全国第四届脑血管疾病学术会议.各类脑血管疾病诊断要点及临床功能缺损程度评分标准(1995)[J]中华神经科杂志,1996(06).
  • 9张富国.依达拉奉治疗急性脑梗塞40例[J].中国药业,2008,17(3):55-55. 被引量:13
  • 10杨立业,刘相名,孙兵,惠国桢,费俭,郭礼和.Adipose tissue-derived stromal cells express neuronal phenotypes[J].Chinese Medical Journal,2004(3):425-429. 被引量:34

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