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超重、肥胖患者血清抵抗素、脂联素的水平变化 被引量:8

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摘要 目的探讨在超重和肥胖患者血清抵抗素和脂联素的水平及其影响因素。方法 37例正常体重者、21例超重和24肥胖患者常规测量血压、体重、身高,计算体重指数,抽取空腹静脉血检测其血糖、血脂、胰岛素I、L-6、C-反应蛋白、肿瘤坏死因子(TNF)-α、瘦素、脂联素、抵抗素以及服糖后2小时血糖。结果与正常体重人群相比,超重人群中血清抵抗素和脂联素水平正常;在肥胖患者中血清抵抗素水平升高(〔16.03±8.59)vs(10.62±6.97)ng/ml,P=0.037〕,脂联素水平正常。超重人群中,血清抵抗素与脂联素(r=0.473,P=0.030)、年龄(r=0.437,P=0.047)正相关,脂联素与瘦素(r=0.481,P=0.027)正相关;在肥胖人群中,血清抵抗素与年龄(r=0.476,P=0.019)正相关,脂联素与收缩压(r=0.409,P=0.047)、HDL-C(r=0.463,P=0.023)正相关。结论在肥胖患者中,血清抵抗素增高,与年龄有关,脂联素水平正常,与收缩压、HDL-C相关。
出处 《中国老年学杂志》 CAS CSCD 北大核心 2011年第20期3919-3921,共3页 Chinese Journal of Gerontology
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