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^(131)I治疗老年分化型甲状腺癌的疗效 被引量:3

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摘要 目的评价131I治疗老年分化型甲状腺癌(DTC)的治疗效果及应用价值。方法回顾性分析了96例老年DTC根治术后131I治疗效果,根据手术病理、甲状腺吸碘率、Tg、TgAb、肺CT、颈部彩超等因素,采用相对固定剂量法,清甲治疗给予131 I 2.96~4.44 GBq,清灶治疗给予131 I5.55~7.40 GBq,并给予甲状腺激素替代-抑制治疗。随访18~36个月评价疗效。结果 96例131 I治疗老年DTC后,36例治愈,50例有效,10例无效。结论老年DTC不同于中青年DTC,发现晚、预后较差。根治术术后1~2个月行131I清甲成功率较高,明显改善预后,提高生存质量,故老年DTC根治术后行131I内照射治疗具有重要的临床价值。
出处 《中国老年学杂志》 CAS CSCD 北大核心 2011年第20期3924-3925,共2页 Chinese Journal of Gerontology
基金 卫生部吴阶平医学基金资助课题(320.6750.07127)
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  • 1Shaha AR. Prognostic factors in papillary thyroid carcinoma and implications of large nodal metastasis [ J ]. Surgery, 2004,135 : 237 - 239.
  • 2Mazzaferri EL,Jhiang SM. Long-term impact of initial surgical and medical therapy on papillary and follicular thyroid cancer[ J ]. Am J Med, 1994,97:418 - 428.
  • 3Scheumann GF, Gimm K, Wegener G,et al. Prognostic significance and surgical management of locoregional lymph node metastases in papillary thyroid cancer[ J]. World J Surg, 1994,18:559 - 567.
  • 4Kupferman ME, Patterson M, Mandel SJ, et al. Patterns of lateral neck metastasis in papillary thyroid carcinoma[ J]. Arch Otolaryngol Head Neck Surg,2004,130 : 857 - 860.
  • 5Pingpank JF Jr, Sasson AR, Hanlon AL,et al. Tumor above the spinal accessory nerve in papillary thyroid cancer that involves lateral neck nodes: a common occurrence [ J ]. Arch Otolaryngol Head Neck Surg,2002,128 : 1275 - 1278.
  • 6Machens A, Holzhausen H J, Dralle H. The prognostic value of primary tumor size in papillary and follicular thyroid carcinoma [ J ]. Cancer,2005,103:2269 - 2273.
  • 7Davies L,Welch HG.Increasing incidence of thyroid cancer in the United States,1973-2002.J Am Med Assoc,2006,295:2164-2167.
  • 8Cooper DS,Doherty GM,Haugen BR,et al.Management guidelines for patients with thyroid nodules and differentiated thyroid cancer.Thyroid,2006,16:109-142.
  • 9Lundgren CI,Hall P,Dickman PW,et al.Clinically significant prognostic factors for differentiated thyroid carcinoma:a populationbased,nested case-control study.Cancer,2006,106:524-531.
  • 10Jukkola A,Bloigu R,Ebeling T,et al.Prognostic factors in differentiated thyroid carcinomas and their implications for current staging classifications.Endocr Relat Cancer,2004,11:571-579.

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  • 1傅烨生,郝慧钧,张德重,王忠明,耿强.131碘“清甲”治疗分化型甲状腺癌临床研究[J].中国血液流变学杂志,2014(1):153-156. 被引量:4
  • 2王从俊,薛新波,易继林,张爱龙.151例复发性甲状腺癌的临床分析[J].临床外科杂志,2004,12(10):607-608. 被引量:4
  • 3朱瑞森,余永利,陆汉魁,罗全勇,陈立波.分化型甲状腺癌术后^(131)I治疗的必要性[J].上海交通大学学报(医学版),2006,26(9):1042-1043. 被引量:20
  • 4Macdonald W, Armstrong J. Benign struma ovarii in a pa- tient with invasive papillary thyroid eancer:detection with 1-131 SPECT-CT[J]. Clin Nuel Med, 2007,32 (5) : 380- 382.
  • 5Turtle RM,Tala H,Shah J, et al. Estimating risk of re- currence in differentiated thyroid cancer after total thy- roidectomy and radioactive iodine remnant ablation: using response to therapy variables to modify the initial risk es- timates predicted by the new American thyroid associa- tion staging system [J]. Thyroid, 2010, 20 (12): 1341- 1349.
  • 6Siegel R, Ward E, Brawley O, et al. Cancer statistics, 2011 :the impact of eliminating socioeconomic and racial disparities on premature cancer deaths[J]. CA Cancer J Clin,2011,61(4),212-236.
  • 7Cheng SP, Liu CL, Tzen CY, et al. Characteristics of well- differentiated thyroid cancer associated with multinodular goiter[J]. Langenbecks Arch Surg, 2008, 393 (5): 729- 732.
  • 8Nixon IJ,Whitcher MM, Palmer FL, et al. The impact of distant metastases at presentation on prognosis in pa- tients with differentiated carcinoma of the thyroid gland[J]. Thyroid,2012,22(9) :884-889.
  • 9Van Nostrand D. The benefits and risks of 1-131 therapy in patients with well-differentiated thyroid cancer [J]. Thyroid, 2009,19(12): 1381-1391.
  • 10Whitley RJ, Ain KB. Thyroglobulin: a specific serum marker for the management of thyroid carcinoma[J]. Clin Lab Med,2004,24(1) :29-47.

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