摘要
目的评价宫颈脱落细胞学、HPV检测对宫颈癌检测的准确性。方法选取40例拟诊宫颈癌受检者,分别进行宫颈脱落细胞学、HPV检测检测,对两种细胞学方法检测结果进行对比。然后以阴道镜下组织病理学结果作为金标准,比较两种细胞学方法对宫颈癌筛查的准确性进行诊断价值的评价。结果 40例拟诊宫颈癌中,组织病理学确诊阳性36例,阴性4例。宫颈脱落细胞学与HPV检测对于宫颈癌与组织病理学病变检出率比较无统计学意义(P>0.05)。按金标准分别对两种检查结果进行诊断试验评价,检出宫颈癌的灵敏度比较无显著差异(P>0.05),而特异度比较有显著差异(P<0.05)。结论宫颈脱落细胞学与HPV检测对宫颈癌的筛查有较高的检出率,敏感性都比较好,但是特异性都存在不足,在临床上建议共同采用,以提高宫颈癌诊断的准确率。
Objective To evaluate the accuracies of thinprep cytologic test（TCT） and human papillomavirus（HPV） test in diagnosing cervical cancer.Methods Totally 40 cases for cervical cancer diagnosis were selected;TCT and HPV test were applied and comparisons were made between the two cytological methods.The testing accuracies of the two methods were compared according to the gold standard of pathological diagnosis by colposcopy.Results Among the 40 cases,36 cases were confirmed to be positive and 4 cases to be negative through histopathology.No statistical significance in the detection rate was found between the two methods（P〈0.05）.The detection sensitivity of the two methods was of no significant difference according to the evaluation of the gold standard（P〈0.05）,while the specificity of the two methods showed significant differences（P〈0.05）.Conclusion Both TCT and HPV test are having high detection rate and sensitivity in diagnosing cervical cancer,but they are deficient in specificity,therefore,it＇s better to combine the two methods together for application.
出处
《局解手术学杂志》
2011年第6期638-639,共2页
Journal of Regional Anatomy and Operative Surgery
