摘要
目的探讨左氧氟沙星联合传统抗结核药治疗复治菌阳肺结核的临床效果。方法将我院复治菌阳肺结核患者72例随机分为观察组和对照组,对照组给予常规抗结核药治疗,在此基础上观察组给予左氧氟沙星联合治疗,评估两者治疗效果。结果观察组2个月及8个月痰菌阴转率明显高于对照组,两组比较差异具有统计学意义(P<0.05)。8个月时观察组X线胸片病变吸收率明显高于对照组,两组比较差异具有统计学意义(P<0.05)。8个月时观察组空洞改善率明显高于对照组,两组比较差异具有统计学意义(P<0.05)。两组均无明显的治疗副反应产生。结论左氧氟沙星联合传统抗结核药治疗复治菌阳肺结核疗效明确,副作用少,值得应用。
Objective To investigate the effect of levofloxacin in treating cases with retreatment bacterio-positive pulmonary tuberculosis. Methods 72 cases with retreatment bacterio-positive pulmonary tuberculosis were divided into observation group and control group. The two groups received normal antituberculotic treatment, and the observation group received the treatment of normal antituberculotic treatment combined with levofloxacin. Results The sputum negative conversion rate in the observation group after treatment of 2 and 8 months were higher than those in the control group, and there was significant difference between the two groups （P 0.05）. The absorptivity of pathological changes about sternum in the observation group after treatment were higher than those in the control group, and there was significant difference between the two groups （P 0.05）. The improvement rate of cavity in the observation group after treatment were higher than those in the control group, and there was significant difference between the two groups （P 0.05）. There was no significant side-effect in the two groups. Conclusion The effect of levofloxacin in treating cases with retreatment bacterio-positive pulmonary tuberculosis is obvious and the side-effect is few, so it is worthy of application.
出处
《临床医学工程》
2011年第11期1722-1723,共2页
Clinical Medicine & Engineering
关键词
左氧氟沙星
肺结核
痰培养
Levofloxacin
Pulmonary tuberculosis
Sputum culture
