摘要
在碱催化下,由对叔丁基苯酚和甲醛反应合成对叔丁基杯[4]芳烃。加入适量的乙酸乙酯作为带水剂,同时溶剂二苯醚可以循环使用。考察了乙酸乙酯的加入量和二苯醚循环使用次数对产品收率的影响。结果表明,加入乙酸乙酯带水剂,可以提高产品收率,缩短脱水时间,反应易于控制;二苯醚的使用次数对收率也有显著的影响,当第3次使用时,收率提高到73%。此种改进方法可以缩短反应时间、提高产品收率。同时探讨了催化剂K_2CO_3的用量对合成对叔丁基杯[4]芳烃和对叔丁基杯[4]芳烃四乙酸乙酯收率的影响。结果表明,对叔丁基杯[4]芳烃与K_2CO_3的最佳物质的量比为1:11,产品收率达到74%。
p--tert--Butylcalix[4]arene was synthesized by p--tert--butylphenol and aldehyde using alkali as catalyst. An appropriate amount of ethyl acetate was added as a water carrier and the diphenyl ether was recycled as solvent. Amount of ethyl acetate and recycle times of diphenyl ether which effect on the yield of product were investigated. The results show that the addition of ethyl acetate can make the products yield increase, the dehydration time shorten and the reaction control easily. Recycle times of diphenyl ether has significant effect on the products yield. The yield increased to 73% when diphenyl ether was reused 3 times. The improved method can shorten reaction time and increase the yield of products. In addition, the effect of the catalyst K2COs amount on the yield of tetraethyl p--tert--butylcalix[4]arene tetraacetate were discussed. The result shows that the yield of the product can reached 74% when the optimal mole ratio of p-tert--butylcalix[4]arene to catalyst K2CO3 was 1 ： 11.
出处
《石油化工高等学校学报》
CAS
2011年第5期48-52,共5页
Journal of Petrochemical Universities
基金
教育部科学技术研究重点项目(209031)
关键词
芳烃
芳烃四乙酸乙酯
乙酸乙酯
循环利用
二苯醚
p--tert--Butylcalix[4]arene
p--tert--Butylcalix[4]arene tetraacetate
Ethyl acetate
Recycling
Diphenyl ether
