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呋塞米联合小剂量多巴胺治疗小儿顽固性心力衰竭疗效观察 被引量:3

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摘要 目的探讨呋塞米联合小剂量多巴胺治疗小儿顽固性心力衰竭的临床疗效。方法所有患者入院后均给予吸氧、限水钠摄入、饮食控制、休息等一般治疗。同时给予血管紧张素转化酶抑制剂(ACEI)、β-受体阻滞剂、利尿剂、洋地黄等药物,快速心律失常的患者纠正心律失常,合并感染给予抗感染。观察组在上述治疗基础上,呋塞米起始按1mg/kg静脉注射,必要时每隔2h追加1mg/kg。最大剂量可达每日6mg/kg。新生儿应延长用药间隔。多巴胺静脉输注0.5~2.0μg.kg-1.min-1。持续应用3d后观察疗效。结果治疗3d后,观察组临床症状、体征减轻,心功能改善等明显好于对照组,两组比较差异有显著性P<0.01;治疗后两组患者LVEF、LVEDD均有改善,观察组与对照组治疗后比较差异有显著性P<0.05,与本组治疗前比较差异有显著性P<0.05。结论应用呋塞米同时给予小剂量多巴胺,能更好地发挥利尿作用,减轻心脏负荷且没有发现对血压和心率的负面影响,疗效满意,副作用较少。
作者 吴敏
出处 《西南军医》 2011年第6期1042-1043,共2页 Journal of Military Surgeon in Southwest China
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  • 1张萍.6分钟步行试验[J].临床心电学杂志,2007,16(3):236-237. 被引量:58
  • 2Dormans TP, van Meyel J J, Gerlag PG,et al. Diuretic efficacy of high dose furosemide in severe heart failure:bolus injection versus continuous iiffusion [ J ]. J Am Coil Cardiol, 1996,28 ( 2 ) : 376 - 382.
  • 3Pivac N,Rumboldt Z, Sardelie S,et al. Iuretic effects of furosemide infusion versus bolus injection in congestive heart failure[J].Int J Clin Pharmacol lies, 1998,18 ( 3 ) : 121 - 128.
  • 4van Meyel JJ, Smlts P, Dormans T, el al. Continuous infusion of furosemide in the treatment of patients with congestive he.art failure and diuretic resistance[J]. J Intern Meal, 1994,235 (4) :329 -334.
  • 5Maxwell AP, Ong HY, Nicholls DP. Influence of progressive renal dysfunction in chronic heart failure[ J ]. Eur J Heart Fail,2002,4 (2) :125 -130.
  • 6Adams KF,Mathur VS,Gheorghiade M,et al.B-type natriuretic peptide:From bench to bedside[J].American Heart Journal,2003,145 (2):534-546.
  • 7Bettencourt PM.Clinical usefulness of B-type natriuretic peptide measurement:present and future perspectives[J].Heart,2005,91(11):1489-1494.
  • 8Hartmann F,Packer M,Coats AJ,et al.Prognostic impact of plasma N-terminal pro-brain natriuretic peptide in severe chronic congestive heart failure:A substudy of the carvedilol prospective randomized cumulative survival(COPERNICUS) Trial[J].Circulation,2004,110(13):1780-1786.
  • 9Bettencourt P,Azevedo A,Pimenta J,et al.N-terminal-pro-brain natriuretic peptide predicts outcome after hospital discharge in heart failure patients[J].Circulation,2004,110(15):2168-2174.
  • 10Domans TP,van Meyel JJ,Gerlag PG,et al.Diuretic efficacy of high dose furosemide in severe heart failure:bolus injection versus continuous infusion.Jam Coll Cardiol,1996,28(2):376-382.

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