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全氟化碳乳剂对肺缺血再灌注损伤的保护机制及其研究进展 被引量：3

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摘要 肺缺血再灌注损伤(LIRI)存在于心脏手术、胸外科手术术后以及出血性休克的过程中尤其在肺移植手术术后,其对患者的恢复存在极大的影响;全氟化碳乳剂(Perfluorocarbon emulsion,PFCF)通过其具有较高的携O2及CO2的能力及高比重的特性,扩张肺泡、调节肺通气/血流比、改善肺气体交换、抗炎等作用保护肺功能;本文就PFCF的性质及其在肺缺血再灌注损伤中的应用进行综述。
作者 何开明 戴天阳
机构地区 泸州医学院附属医院胸心外科
出处 《西南军医》 2011年第6期1078-1080,共3页 Journal of Military Surgeon in Southwest China
关键词 肺缺血再灌注损伤 全氟化碳乳剂
分类号 R655.3 [医药卫生—外科学]
  • 相关文献

参考文献19

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二级参考文献3

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共引文献2

同被引文献38

  • 1赵健,单晓茜,盛燕,吴凡,袁媛,刘昌胜.纳米微囊型血液代用品的制备及体内外血液安全性评价[J].生物医学工程学杂志,2008,25(3):584-588. 被引量：2
  • 2许蜀闽,王培勇,马红英.连二亚硫酸钠在建立培养细胞的无氧环境中的应用[J].第三军医大学学报,2005,27(4):359-360. 被引量：66
  • 3王瑾.全氟化碳对心脏再灌注损伤的保护[J].世界急危重病医学杂志,2006,3(5):1507-1511. 被引量：4
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  • 7Kinasiewicz A,Smietanka A,Gajkowska B,et al.Impact of oxygenation of bioartificial liver using perfluorocarbon emulsion perftoran on metabolism of human hepatoma C3A cells.Artif Cells Blood Substit Immobil Biotechnol,2008,36(6):525-534.
  • 8Fischer S,Hopkinson D,Liu M,et al.Raffinose improves 24-hour lung preservation in low potassium dextran glucose solution:a histologic and ultrastructural analysis.Ann Thorac Surg,2001,71 (4):1140-1145.
  • 9Gale SC,Gorman GD,Copeland JG,et al.Perflubron emulsion prevents PMN activation and improves myocardial functional recovery after cold ischemia and reperfusion.J Surg Res,2007,138(1):135-40.
  • 10Ma X,Xu D,Ai Y,et al.Fas inhibition attenuates lipopolysaccharide-induced apoptosis and cytokine release of rat type Ⅱ alveolar epithelial cells.Mol Biol Rep,2010,37(7):3051-3056.

引证文献3

二级引证文献5

西南军医
2011年 第6期

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