摘要
A process for ammoxidation of 2, 4-dichlorotoluene to prepare 2, 4-dichlorobenzonitrile which is a key intermediate of organic synthesis was studied. Having appraised and screened catalysts on an apparatus of umicroreactor-chromatograghy', the further experiments confirming the catalyst and find-ing the optimum technological conditions were carried out by using a fixed-bed reactor made of quartz (30mm inside diameter). The influence of temperature, the ratio of ammonia, the ratio of air and the space velocity of catalyst upon the conversion, molar yield and selectivity of the reaction were observed, respec-tively. Using catalyst of DC124, on the suitable conditions, the highest conversion is 98. 1 %, molar yield is 89. 5%. The 2, 4-dichlorobenzonitrile obtained is white sheet or needle crystal with the purity hlgher than 99%. The effect of two chlorine atoms at 2, 6 or 2,4 position on the reaction is discussed based on the research of the ammoxidation of 2, 6-dichlorotoluene and 2,4-dichlorotoluene.
A process for ammoxidation of 2, 4-dichlorotoluene to prepare 2, 4-dichlorobenzonitrile which is a key intermediate of organic synthesis was studied. Having appraised and screened catalysts on an apparatus of umicroreactor-chromatograghy', the further experiments confirming the catalyst and find-ing the optimum technological conditions were carried out by using a fixed-bed reactor made of quartz (30mm inside diameter). The influence of temperature, the ratio of ammonia, the ratio of air and the space velocity of catalyst upon the conversion, molar yield and selectivity of the reaction were observed, respec-tively. Using catalyst of DC124, on the suitable conditions, the highest conversion is 98. 1 %, molar yield is 89. 5%. The 2, 4-dichlorobenzonitrile obtained is white sheet or needle crystal with the purity hlgher than 99%. The effect of two chlorine atoms at 2, 6 or 2,4 position on the reaction is discussed based on the research of the ammoxidation of 2, 6-dichlorotoluene and 2,4-dichlorotoluene.
