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陈旧性心肌梗塞患者凝血纤溶状态的研究 被引量:9

Study of Coagulation and Fibrinolysis in Patients with Old Myocardial Infarction
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摘要 测定了16例陈旧性心肌梗塞(OldMyocardialInfarction,OMI)患者凝血、纤溶分子标记物及血栓弹力图,并与正常人及急性心肌梗塞(AcuteMyocardialInfarction,AMI)患者作了比较。结果表明:OMI患者凝血激活分子标志物凝血酶─抗凝血酶Ⅲ复合物及血纤维蛋白肽A均高于正常对照组(P<0.05),但低于AMI组(P<0.05),OMI组纤溶指标D—D二聚体高于正常对照组(P<0.05),但低于AMI组(P<0.05)、OMI组其TEG之r值及k值较正常对照组明显缩短(P<0.05),而与AMI组无差异。OMI组Ma值大于正常对照组(P<0.01),而与AMI组无差异。 Thrombin-antithrombin Ⅲ complex (TAT), Fibrin peptide A (FPA) .D-D dimer. a2-PI andThromboelastograph (TEG) in OMI patients were detected and the results were compared with patients withAMI and normal control. It was shown that the levels of TAT.FPA and D-D dimer in OMI were significantlyhigher than those in normal control (P<0. 05) and lower than those in AMI(P<0. 05). The r value and kvalue in OMI were significanly shorter than those in normal control (P< 0. 05), while Ma value was significantly higher than that in normal control (P< 0.01 ). The results suggest that the coagulation activationand fibrin formation exist in the patients with OMI.
出处 《华中科技大学学报(医学版)》 CAS CSCD 1998年第4期277-279,共3页 Acta Medicinae Universitatis Scientiae et Technologiae Huazhong
基金 国家"八五"攻关课题!85-915-03
关键词 冠心病 冠状动脉 血栓形成 纤维蛋白溶解 coronary heart disease coronary artery thrombosis fibrinolysis
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