The QSAR Research of Pyrrolobenzothiazepinones and Pyrrolobenzo-xazepinones-Novel and Specific Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors

The QSAR Research of Pyrrolobenzothiazepinones and Pyrrolobenzo- xazepinones-Novel and Specific Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors

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摘要 The quantitative structural parameters and activity relationship of pyrrolobenzothiazepin-ones and pyrrolobenzoxazepinones' inhibitory activities on HIV-1 reverse transcriptase (RT) was studied. A good relationship has been built. The quantitative structural parameters and activity relationship of pyrrolobenzothiazepin-ones and pyrrolobenzoxazepinones' inhibitory activities on HIV-1 reverse transcriptase (RT) was studied. A good relationship has been built.

作者 Wang, JM Hou, TJ Li, YY Xu, XJ

机构地区 BEIJING UNIV

出处《Chinese Chemical Letters》 SCIE CAS CSCD 1997年第10期889-892,共4页 中国化学快报（英文版）

分类号 O621 [理学—有机化学]

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1Xin CHEN,Lin WANG,Zhi Zhong ZHAO,Xing Quan ZHANG,Xiang Hong CHEN,Hong Shan CHEN(Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050 Institute of Medicinal Biotechnology, Chinese Academy of M.Synthesis of Novel Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors-1-(3-Phthalimido-2-oxobutyl)-4-Substituted-phenylpiperazines[J].Chinese Chemical Letters,2000,11(7):571-572.
2殷丽琴,余仕问,姚凌峰,何严萍,谢小光.QSAR Studies on 6-(1-Naphthylmethyl) Substituted S-DABO Derivatives as Novel Non-nucleoside HIV-1 Reverse Transcriptase Inhibitors[J].Chinese Journal of Structural Chemistry,2008,27(10):1214-1222. 被引量：2
3Ting Jun HOU,Jun Mei WANG,You Yong LI,Xiao Jie XU(Chemistry department, Beida-Jiuyuan Molecular Design Laboratory, Peking University,Beijing 100871).Application of Genetic Algorithm to the QSAR Research of Pyrrolobenzothiazepinones and Pyrrolobenzoxazepinones-Novel and Specific Non-Nucleoside HIV-1 Reverse Transcription Inhibitors[J].Chinese Chemical Letters,1998,9(7):651-654.
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Chinese Chemical Letters

1997年第10期

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The QSAR Research of Pyrrolobenzothiazepinones and Pyrrolobenzo-xazepinones-Novel and Specific Non-Nucleoside HIV-1 Reverse Transcriptase Inhibitors

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