摘要
目的回顾分析近6年宁夏地区新发前列腺癌的资料,为提高我区前列腺癌筛查和临床诊治水平提供依据。方法收集2005年1月-2010年11月初次就诊于宁夏医科大学总医院泌尿外科的245例宁夏籍新发前列腺癌患者临床资料进行分析。结果我区新发前列腺癌患者呈逐年增高趋势。全组患者中位发病年龄为72.8岁,确诊时中位血清PSA值为31.9ng.mL-1。临床表现为下尿路症状186例(75.9%)、骨痛35例(14.3%)和血尿32例(13.1%),直肠指检质硬或有明显硬结155例(63.3%)。患者中有167例由前列腺穿刺活检病理确诊,26例为偶发癌,67例有组织病理Gleason评分。172例(70.2%)在确诊时已属中晚期前列腺癌;出现远处转移64例,其中骨转移55例(22.4%)。245例前列腺癌患者中行内分泌治疗187例,前列腺癌根治术8例,膀胱造瘘术12例,其余38例转外院治疗情况不详。结论我区新发前列腺癌患者呈逐年增高趋势,大部分患者在确诊时已属前列腺癌中晚期,内分泌治疗为主要治疗方法,前列腺癌根治术比例小,放射治疗尚未开展,我区前列腺癌的筛查和临床诊治水平有待提高。
Objective To analyze the information of past six years,new-onset prostate cancer in the Ningxia and to provide the basis for clinical diagnosis and treatment.Methods 245 cases of new-onset prostate cancer enrolled from January 2005-November 2010 in Ningxia Medical University Hospital were reviewed.Results The overall median age was 72.8 years,median serum PSA at diagnosis was 31.9ng/mL.Clinical manifestations showed lower urinary tract symptoms 186 cases（75.9%）,bone pain in 35 patients（14.3%） and hematuria in 32 cases（13.1%）,digital rectal examination or a clear hard induration 155 cases（63.3%）.167 cases were diagnosed by prostate needle biopsy including 26 cases of sporadic cancer and 67 cases of organized pathologic Gleason score.172 cases（70.2%） were diagnosed at advanced stage in prostate cancer in which distant metastasis 64 cases and bone metastasis 55 cases（22.4%）.Of 245 patients,187 cases were performed endocrine therapy Bank,8 cases got radical prostatectomy,12 cases took bladder fistulization and the remaining 38 cases were transferred outside the hospital.Conclusion The majority of prostate cancer patients were diagnosed at advanced stage.Endocrine therapy was the main treatment and radical prostatectomy carried out less.Prostate cancer screening,clinical diagnosis and treatment need to be improved in Ningxia.
出处
《宁夏医科大学学报》
2011年第10期934-936,共3页
Journal of Ningxia Medical University
基金
宁夏自然科学基金项目(NZ08103)
关键词
前列腺癌
临床调查
宁夏
prostate cancer
epidemiological characteristics
Ningxia
