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妊娠高血压综合征患者超敏C-反应蛋白水平变化的意义 被引量:7

Study of the implications for the serum levels of high sensitivity C reactive protein in pregnancy induced hypertension
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摘要 目的研究妊娠血清超敏C-反应蛋白(hs-CRP)水平与妊娠高血压综合征(PIH)的关系及临床意义。方法选择39例PIH患者(PIH组,另分为妊娠高血压亚组16例、子痫前期亚组17例和子痫亚组6例)与同期18例妊娠健康妇女(正常对照组)的hs-CRP水平比较,来判断其变化的意义。结果 PIH组hs-CRP血清水平高于正常对照组(P<0.05),妊娠高血压亚组、子痫前期亚组、子痫亚组hs-CRP血清水平呈逐渐增加趋势(P<0.05)。结论 PIH患者血清hs-CRP水平高于健康孕妇,且随着病情的进展,血清hs-CRP水平亦呈逐渐升高趋势。检测血清hs-CRP水平变化对PIH患者病情的评定起指导作用。 Objective To investigate the relationship between the serum level of high sensitivity C reactive protein (hs-CRP) and pregnancy induced hypertension(PIH) and explore its clinical significance. Methods Compared the serum levels of hs-CRP between 39 cases patienis with PIH (PIH group, divided into PIH subgroup of 16 cases,preeclampsia subgroup of 17 cases and eclampsia subgroup of 6 cases)and 18 cases of healthy pregnant women( control group)in same period to determine the significance of the change. Results The hs-CRP serum levels of PIH group was higher than that in control group ( P 〈 0.05 ), the serum levels of hs-CRP in PIH subgroup, preeclampsia subgroup and eclampsia subgroup showed a gradual increasing trend ( P 〈 0.05 ). Conclusion The results suggest that the serum levels of hs-CRP is increased with the progress of the disease. It plays an important role in the occurrence.
作者 鲍永梅
出处 《临床合理用药杂志》 2011年第21期43-44,共2页 Chinese Journal of Clinical Rational Drug Use
关键词 妊娠高血压综合征 超敏C-反应蛋白 意义 Pregnancy induced hypertension High sensitivity C reactive protein Significance
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参考文献2

  • 1Kocyigit Y,Atamer Y,Atamer A,et al.Changes in serum levels of leptin,cytokines and lipoprotein in pre-eclamptic an normotensive pregnant women[J].Gynecol Endocrinol,2004,19(5):267.
  • 2Buck C,Bundschu J,Gallati H,et al.Interleukin-6:a sensitive parameter for early diagnosis of neon at al bacterial infection[J].Pediatrics,2007,93(7):54-58.

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