摘要
目的探讨早期干预对新生儿中、重度缺氧缺血性脑病(HIE)预后的影响。方法将2009年5月至2010年5月在商丘市第一人民医院治疗的85例足月中重度HIE患儿分为早期干预组49例和非干预组36例,对干预组进行系统的早期干预,均于出生后3,6,9,12月龄对两组患儿进行智能发育随访和评估。结果干预组平均智能发育指数(MDI)高于非干预组(P<0.05);干预组平均运动发育指数(PDI)除3个月时差异无统计学意义外,其余各时点均高于非干预组(P<0.05),非干预组后遗症发生率明显高于干预组(P<0.05)。结论对HIE患儿早期给予持续的干预,能有效地促进智力发育,改善预后,降低后遗症的发生率,是提高其生活质量的有效方法。
Objective To study the effect of early intervention on neonates with hypoxic ischemic encephalopathy （HIE）. Methods A total of 85 neonates patients with medium and severe HIE were enrolled from our hospital from may 2009 to may 2010, and they were divided into 49 cases in the intervention group and 36 cases in the untreated group, early systemic intervention was done for intervention group, all subjects were followed up and examined in regard to intellectual development at 3,6,9, and 12-month age at birth, Results Of the intervention group the average intellectual development index is higher than untreated group （ P 〈 0.05 ） , except 3-month age at birth, compared the intervention group the average motor development index is higher than untreated group（ P 〈 0.05 ）, The incidence of sequelae in untreated group was significantly higher than in intervention group. Conclusions Early continuous intervention can efectivelyfacilitate the intelligence development, improve prognosis and reduce the incidence rate for sequela, thus acting as one of the potent methods for treating HIE neonat.
出处
《中华脑血管病杂志（电子版）》
2011年第5期37-39,共3页
Chinese Journal of Cerebrovascular Diseases(Electronic Edition)
关键词
缺氧缺血性脑病
早期干预
新生儿
Hypoxic ischemic encephalopathy
Early intervention
Neonate
