摘要
背景:氟硅酮丙烯酸脂透气性材料成为制作角膜塑形镜的理想材料,其对眼屈光和眼生理的影响受到关注。目的:研究角膜塑形术控制近视发展的临床效果及安全性。方法:观察18例35眼佩戴1年角膜塑形镜的青少年中、低度近视裸眼视力、屈光度变化、眼轴长度、角膜内皮计数、眼压、角膜Q值等变化。结果与结论:1年后裸眼视力与佩戴前矫正视力比较差异无显著性意义(t=-0.27、P=0.78);佩戴前后1年屈光度、眼轴长度、角膜内皮计数、眼压比较差异无显著性意义(t=1.37、P=0.18;t=-0.94、P=0.35;t=-0.52、P=0.6;t=1.00、P=0.32);佩戴前后1年角膜Q值比较差异有显著性意义(t=-8.03、P=0.00)。提示氟硅酮丙烯酸脂透气性材料角膜塑形镜控制近视安全、有效,对眼生理影响小。
BACKGROUND： Fluorosilicone acrylate is a perfect plastic material for orthokeratology, and its influence on diopter and physiology of the eye is attracted. OBJECTIVE： To study the clinical safety and effects of orthokeratology to control myopia development. METHODS： The clinical data of 18 patients （35 eyes） wearing orthokeratology contact lens （Ortho-k CL） for 1 year were analyzed in low-and middle-degree myopia of the teenage, including uncorrected visual acuity （UCVA）, diopter, axial length, the number of corneal endothelial cells, intraocular pressure, cornea Q value. RESULTS AND CONCLUSION： There was no significant difference in the UCVA after wearing Ortho-k CL for 1 year to corrected visual acuity before wearing （t=-0.27, P=0.78）. Compared to before wearing Ortho-k CL, there was no significant difference in diopter, axial length, the number of corneal endothelial cells, intraocular pressure at 1 year after wearing （t=1.37, P=0.18; t=-0.94, P=0.35; t=-0.52, P=0.6; t=1.00, P=0.32）. There was significant difference in cornea Q value （t=-8.03, P=0.00） between before and after wearing Ortho-k CL. Results showed that fluorosilicone acrylate Ortho-k CL is effective and safe to control myopia development with little influence on eye physiology.
出处
《中国组织工程研究与临床康复》
CAS
CSCD
北大核心
2011年第42期7813-7816,共4页
Journal of Clinical Rehabilitative Tissue Engineering Research
