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低蛋白血症对重度子痫前期的临床意义 被引量:6

Clinical significance of hypoproteinemia for severe preeclampsia
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摘要 ①目的探讨重度子痫前期并发低蛋白血症对妊娠结局的影响。②方法回顾性分析我院收治的163例重度子痫前期患者的临床资料,以血浆白蛋白30g/L为界将病例组分为非低蛋白血症组(A组)70例和低蛋白血症组(B组)93例,比较两组间孕妇的并发症情况、新生儿出生体重、新生儿窒息、FGR及低体重儿等方面的差异。③结果低蛋白血症组孕妇住院孕周及分娩孕周显著低于非低蛋白血症组,而入院血压、发生并发症的例数显著高于非低蛋白血症组(P<0.05);低蛋白血症组新生儿出生体重显著低于非低蛋白血症组,而新生儿窒息、FGR及低体重儿显著高于非低蛋白血症组(P<0.05)。④结论低蛋白血症对重度子痫前期的孕妇及围生儿均有不同程度的危害,血浆白蛋白的变化对重度子痫前期具有非常重要的临床意义,可作为一种监测指标指导病情监护和治疗。 Objective To explore the influence severe preeclampsia complicated by hypopreteinemia to the delivery outcome.Methods Reviewed the clinical data of the 163 inpatients in our hospital for severe preeclampsia,and divided them into two groups according to the plasma albumin level(30g/L),with 70 inpatients in group A named non-hypopreteinemia,and 93 inpatients in group B named hypoporteinemia.We compared the difference in complication situation,neonatal birth weight,neonatal asphyxia,FGR and infant of low-birth weight.Results Pregnant women from hypoporteinemia group showed much earlier in gestational weeks than women from non-hypoporteinemia group in terms of being hospitalized and delivery(P〈0.05).And neonatal birth weight from the hypoporteinemia group was significantly lower than the non-hypoporteinemia group.Consequently their data about neonatal asphyxia,FGR and infant of low-birth weight showed much lower level than the other group(P〈0.05).Conclusion Hypoporteinemia various hazards to pregnant women and prenatal perinatal fetus of severe preeclampsia and it strongly affects the delivery outcome.Therefore the changes of plasma albumin level have very important clinical meanings to the severe preeclampsia patients,which should serve as the standards of monitoring patients' conditions and treatments.
出处 《华北煤炭医学院学报》 2011年第6期745-746,共2页 Journal of North China Coal Medical College
关键词 子痫前期 重度 低蛋白血症 妊娠结局 Preeclampsia.Severe.Hypoporteinemia.Delivery outcome
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