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RCC1、EGFR与K-ras在NSCLC治疗中的进展 被引量:2

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摘要 肺癌居癌相关性死因首位,非小细胞肺癌(NSCLC)占肺癌的80%-85%,非小细胞肺癌的发病率和死亡率呈上升趋势,化疗仍是晚期NSCLC最重要的治疗方式,而其标准一线化疗方案(含铂的第三代二联化疗方案)的有效率仅为25%-35%。总体而言,肺癌患者的预后仍较差。当今,NSCLC患者个体化治疗中,利用分子标志物预测预后和指导治疗成为研究热点,通过检测分子标志物指导个体化治疗,能够选择最有效的治疗策略,使疗效最大化,
机构地区 承德医学院
出处 《承德医学院学报》 2011年第4期426-430,共5页 Journal of Chengde Medical University
关键词 ERCC1 EGFR K—ras NSCLC
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