摘要
目的评价联合检测胃癌相关抗原MG7(MG7-Ag)和癌胚抗原(CEA)对鉴别良恶性胃溃疡的临床价值和可行性。方法分析180例胃溃疡患者的胃黏膜MG7-Ag和血清CEA检测结果。结果 75例恶性溃疡患者中MG7-Ag和CEA阳性表达分别为67例和54例,两者皆表达阳性为50例,联合检测结果阳性71例;105例良性溃疡患者中MG7-Ag和CEA阳性表达分别为40例和24例,两者皆表达阳性为8例,联合检测结果阳性55例。两组差异有统计学意义(P<0.05)。结论 MG7-Ag和CEA联合检测有利于鉴别良恶性胃溃疡。
Objective To evaluate the clinical value and the possibilities of measuring the gastric cancer-associated antigen MG7 （MG7-Ag）and carcinoembryonic antigen（ CEA ）to distinguish malignant ulcer from benign one. Methods Expression of mucosal MG7-Ag and serum CEA of 180 gastric ulcer patients were all analyzed. Results 67 and 54 cases of 75 malignant gastric ulcer patients showed single positive of mucosal MG7-Ag and serum CEA,50 cases both positive,and 71 cases positive in combined determination. While,40 and 24 cases of 105 benign gastric ulcer patients showed single positive of mucosal MG7-Ag and serum CEA,8 cases both positive,and 55 cases positive in combined determination （P〈0.05）. Conclusion Combined determination of mucosal MG7-Ag and serum CEA is useful for distinguishing malignant ulcer from benign one.
出处
《中国现代医生》
2011年第34期88-89,共2页
China Modern Doctor
关键词
人胃癌相关抗原
胃蛋白酶原类
胃溃疡
Gastric cancer-associated antigen MG7
Carcinoembryonic antigen
Gastric ulcer
