摘要
水通道蛋白(AQP)是一类专门运输水的跨膜蛋白,广泛存在于哺乳动物和植物细胞膜上。水在泌尿系统中的吸收和排泄对整个机体的水平衡起着非常重要作用。在人体,多数疾病导致的肾脏损害会引起肾脏对水处理能力的下降;多种身体功能变化能影响到泌尿系统中AQP的表达。AQP家族中对AQP1的结构和功能研究,一直是近年来的研究热点,现对AQP1在泌尿系统中的表达情况的研究进展进行综述。
Aquaporins（AQP） is a kind of special transmembrane protein that transport water,which widely exist in cell membrane of mammals and plants.Water is very important to the human body,and it plays a very important role in the absorption and excretion of urinary system and maintains the water balance of the body,many diseases can cause kidney damage so as to reduce the ability to water treatment of kidney,and the function of body changes can affect AQP expression of urinary system.The structure and function of AQP1 has been the most hotspot in recent years.This paper as follows reviewed for the research of the expression of AQP1 in urinary system.
出处
《实用儿科临床杂志》
CAS
CSCD
北大核心
2011年第23期1836-1839,共4页
Journal of Applied Clinical Pediatrics
