摘要
目的:探讨还原型谷胱甘肽在非酒精性脂肪肝患者治疗中的作用,为临床治疗提供数据支持。方法:将2009年1月～2011年1月我院收治的224例非酒精性脂肪肝患者随机分为观察组和对照组,每组各112例,观察组采用还原型谷胱甘肽联合非诺贝特治疗,对照组采用非诺贝特治疗,治疗6个月后比较两组治疗效果。结果:经过6个月治疗两组患者肝功能指标和血脂水平均明显下降。观察组总有效率为92.86%,对照组总有效率为81.25%,组间比较差异有统计学意义(χ2=4.692,P<0.05)。结论:在常规治疗的基础上联合应用还原型谷胱甘肽治疗非酒精性脂肪肝可有效提高疗效,值得临床推广。
Objective： To study the effect of Reduced Glutathione in patients with nonalcoholic fatty liver disease,to provide data support for clinic.Methods： 224 patients with nonalcoholic fatty liver disease from January 2009 to January 2011 in our hospital were randomly divided into observation group and control group,with 112 cases in each group.The observation group was given Reduced Glutathione combined with Fenofibrate,and the control group was given Fenofibrate.After treatment for 6 months,the therapeutic effect was compared between the two groups.Results： After treatment for 6 months,the liver function index and lipid levels of the two groups were all significantly decreased.The total effective rate of the observation group was 92.86% in the control group and 81.25% in the control group,the differences between groups were statistically significant（χ2=4.692,P0.05）.Conclusion： The application of Reduced Glutathione based on routine treatment in patients with nonalcoholic fatty liver disease can effectively enhance the curative effect,and is worthy of clinical promotion.
出处
《中国医药导报》
CAS
2011年第35期84-85,共2页
China Medical Herald
