摘要
目的:研究血清钙离子浓度与老年肺炎患者的严重程度及预后的关系。方法:按照脓毒症的诊断标准将入住急诊ICU的老年肺炎患者206例,分为脓毒症组(155例)和非脓毒症组(51例),脓毒症组又按照预后分为存活组(91例)和死亡组(64例),分别测定血清钙离子浓度、血浆白蛋白、C-反应蛋白(CRP)、血白细胞计数等有关的实验室指标,比较2组指标的差别。结果:脓毒症组中血清钙离子浓度较非脓毒症组降低,CRP、血白细胞计数较非脓毒症组升高(P<0.01);亚组分析中,死亡组中血清钙离子浓度较存活组降低(P<0.01),CRP较存活组升高(P<0.05),血白细胞计数两组比较无明显差异(P>0.05);血清钙离子浓度与血浆白蛋白的浓度呈高度正相关。结论:血清钙离子浓度对判断老年肺炎患者的预后有一定的临床意义。
Objective: To investigate the relationship of serum calcium with the severity of disease and prognosis in geriatric patients with pneumonia. Methods: 206 elderly patients with pneumonia admitted to EICU in our hospital were divided into two groups: sepsis group (n=155) and nonsepsis group (n=51). Patients in sepsis group were divided into two subgroups: survival group (n=91) and death group (n=64).Serum calcium, plasma albumin, C-reactive protein and leukocyte count were measured. Results: Compared with nonsepsis group, serum calcium was decreased in sepsis group (P〈0.01). C-reactive protein and leukocyte count in sepsis group were heightened (P〈0.01). Compared with survival group, serum calcium was much lower in death group (P〈0.01). C-reactive protein was higher in death group (P〈0.05). Leukocyte counts were similar in the two subgroups (P〉0.05). There was a positive correlation between serum calcium and plasma albumin. Conclusion: Serum calcium can be helpful to predict the prognosis of geriatric people with pneumonia.
出处
《现代生物医学进展》
CAS
2011年第23期4475-4477,共3页
Progress in Modern Biomedicine