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血钙对老年肺炎患者的严重程度及预后的影响 被引量:7

Influence of serum Calcium with Severity and Prognosis in Elderly Pneumonia Patients
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摘要 目的:研究血清钙离子浓度与老年肺炎患者的严重程度及预后的关系。方法:按照脓毒症的诊断标准将入住急诊ICU的老年肺炎患者206例,分为脓毒症组(155例)和非脓毒症组(51例),脓毒症组又按照预后分为存活组(91例)和死亡组(64例),分别测定血清钙离子浓度、血浆白蛋白、C-反应蛋白(CRP)、血白细胞计数等有关的实验室指标,比较2组指标的差别。结果:脓毒症组中血清钙离子浓度较非脓毒症组降低,CRP、血白细胞计数较非脓毒症组升高(P<0.01);亚组分析中,死亡组中血清钙离子浓度较存活组降低(P<0.01),CRP较存活组升高(P<0.05),血白细胞计数两组比较无明显差异(P>0.05);血清钙离子浓度与血浆白蛋白的浓度呈高度正相关。结论:血清钙离子浓度对判断老年肺炎患者的预后有一定的临床意义。 Objective: To investigate the relationship of serum calcium with the severity of disease and prognosis in geriatric patients with pneumonia. Methods: 206 elderly patients with pneumonia admitted to EICU in our hospital were divided into two groups: sepsis group (n=155) and nonsepsis group (n=51). Patients in sepsis group were divided into two subgroups: survival group (n=91) and death group (n=64).Serum calcium, plasma albumin, C-reactive protein and leukocyte count were measured. Results: Compared with nonsepsis group, serum calcium was decreased in sepsis group (P〈0.01). C-reactive protein and leukocyte count in sepsis group were heightened (P〈0.01). Compared with survival group, serum calcium was much lower in death group (P〈0.01). C-reactive protein was higher in death group (P〈0.05). Leukocyte counts were similar in the two subgroups (P〉0.05). There was a positive correlation between serum calcium and plasma albumin. Conclusion: Serum calcium can be helpful to predict the prognosis of geriatric people with pneumonia.
出处 《现代生物医学进展》 CAS 2011年第23期4475-4477,共3页 Progress in Modern Biomedicine
关键词 老年 肺炎 血清钙离子浓度 预后 Elderly Pneumonia Serum calcium Prognosis
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参考文献19

  • 1李玉芝,李汝勇,张春亮.脓毒症患者血清游离钙水平测定及与预后的关系[J].山东医药,2010,50(23):23-25. 被引量:10
  • 2Muthuraj M, Kamatchiyammal S, Usharani B,et al. Serum Zinc, Calcium and Albumin Levels in Pulmonary Tuberculosis Patients Co-Infected with HIV [J]. Global Journal of Biotechnology & Biochemistry ,2010,5 (1): 27-35.
  • 3代冰,于娜,王玮,王海龙,赵洪文,康健.新型甲型H1N1流感住院患者疾病严重程度和死亡的危险因素分析[J].中国医科大学学报,2010,39(7):558-560. 被引量:3
  • 4Levy MM,Fink Mp,Marshall Jc, et al.2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference [J].Crit Care Med,2003,31(4): 1250-1256.
  • 5Nakajima N,Aiba M,Fukuda Y,et al.Causes of death in hospitalized elderly patients[J].Nippon Ronen lgakkai Zasshi,2009,46(1):71-78.
  • 6周高速,周荣斌,程霞.脓毒症预警指标[J].中国急救医学,2007,27(9):848-851. 被引量:17
  • 7Dilli D,Oguz SS,Dilmen U,et al.Predictive values of neutrophil CD64 expression compared with interleukin-6 and C-reactive pro tein in early diagnosis of neonatal sepsis [J].J Clin Lab Anal, 2010,24(6): 363-370.
  • 8Gumani PK, Patel GP,Crank CW,et al.Irnpact of the implementation of a sepsis protocol for the management of fluid-refractory septic shock: A single-center, before-and-atier study [J].Clin Ther,2010,32 (7): 1285-1293.
  • 9Valencia M,Badia J,Cavaleanti M,et al. Pneumonia Severity Index Class V Patients With Community-Acquired Pneumonia Characteristics,Outcomes, and Value of Severity Scores [J]. CHEST, 2007,132(2): 515-522.
  • 10毛亚伦,刘东海,张顺.重症感染患者红细胞膜钙泵活性及钙离子浓度测定及其临床意义[J].浙江医学,2001,23(11):669-670. 被引量:4

二级参考文献85

  • 1李擎天 ,褚嘉祐 ,郭晓奎 .hepcidin、铁代谢与感染[J].国外医学(微生物学分册),2004,27(6):20-21. 被引量:3
  • 2王清江,张淑英,郭春燕.呼吸道感染与微量元素关系的研究[J].现代康复,1998,2(11):1268-1269. 被引量:3
  • 3杨五一,王洁华,徐文静.重症肺炎合并低钠血症34例分析[J].浙江医学,1996,18(3):160-161. 被引量:5
  • 4左启华 林庆 等.高热惊厥(400例临床分析与远期随访)[J].中华儿科杂志,1978,16(1):35-35.
  • 5白耀华.新的肥胖诊断标准.国外医学:内科学分册,2002,29(4):178-178.
  • 6Levy MM,Fink MP,Marshall JC,et al.2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference[J].Crit Care Med,2003,31(4):1250-1256.
  • 7Muller B,Becker KL,Kranzlin M,et al.Disordered calcium homeostasis of sepsis:associati on with calcitonin precursors[J].Eur J Clin lnvest,2000,30(9):823.
  • 8Hasthacka J,Pettila V.Prevalence and predictive value of ionized hypocalcemia among critically ill patients[J].Acta Anaesthesiol Scand,2003,47(10):1264-1269.
  • 9Becker KL,Snider R,Nylen ES.Procalcitonin in sepsis and systemic inflammation:a harmful biomarker and a therapeutic target[J].Br J Pharmacol,2010,159(2):253-264.
  • 10Sayeed MM.Signaling mechanisms of altered cellular responses in trauma,burn,and sepsis:role of Ca2+[J].Arch Surg,2000,135(12):1432-1442.

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