摘要
用微电极记录脊髓背角会聚神经元单细胞活动,研究外周感受野的变化。诱导刺激感受野和特定非感受野(距感受野3~4 cm 同一块肌肉两端)后,不仅感受野刺激发生激活反应,其特定非感受野刺激也能激活该神经元。用肌松剂后这种扩大的感受野反应消失,表明外周感受野能被条件刺激扩大,这种扩大与骨骼肌兴奋时的电及机械效应有关。
Recordings were made from neurons with peripheral excitatory receptive fields on the ipsilateral hindpaw in the lumbar dorsal horn of anaesthetized rats.These neurons were excited by the stimulation in the receptive fields.Testing stimulation of special non receptive fields could activate the neuronal responses after conditioning stimulation in the receptive fields (delay 450 ms).These enlargement responses of receptive fields disappeared during intravenous injection of flaxedil.These results show conditioning stimulation may enlarge peripheral excitatory receptive fields of convergent neurons,which is a relation with the muscular normal function.
基金
国家自然科学基金!(39170894)
国家攀登计划资助
关键词
会聚神经元
外周感受野
脊髓背角
条件刺激
convergent neurons
enlargement of receptive field
conditioning stimulation