摘要
目的调查出生体质量的分布情况及影响因素,探讨低出生体质量危险因素的聚集与低出生体质量危险性的关联性,为采取干预措施提供参考依据。方法采用多阶段分层随机整群抽样方法抽取了来自中国5个省份中5个城市的市区、镇和农村,以2006年1月1日至2008年12月31日出生的婴幼儿及其父母为调查对象。共调查16 954名婴幼儿。采用现况调查方法,使用统一设计的调查表对调查对象进行面访调查。用非条件Logistic回归分析方法估计低出生体质量危险因素的比值比(OR)及其95%可信区间(95%CI)。结果多因素非条件Lo-gistic回归分析结果显示,在调整母亲民族、性别、出生地区等因素后,妊高征、生育胎次≥2次及早产这3个因素均与低出生体质量危险性相关联(均P<0.01);进一步分析危险因素聚集性,在调整母亲民族、性别、出生地区等因素后发现,与无危险因素聚集比较,随着危险因素聚集个数的增加,低出生体质量发生的危险性越高(趋势检验χ2=550.3,P<0.01),早产、胎次≥2、妊高征、孕期贫血这4个危险因素聚集1、2和≥3个的OR值分别为6.311(95%CI为5.024～7.926)、27.49(95%CI为19.80～38.18)和35.04(95%CI为15.66～78.40);危险因素聚集2个及以上的OR值均高于1项的OR值。结论低出生体质量危险性随着危险因素聚集个数的增加而增大。
Objective To explore the incidence rate and risk factors of low birth weight in China,and explore the association between the clustering of influencing factors and low birth weight in China in order to provide some references for preventive measures.Methods We used a random sampling method to choose fields sence from five cities towns and country areas which stand for five regions in China,16 954 infants who were born from Jan 1,2006 to Dec 31,2008 and their parents were enrolled in our survey.We Surveyed face to face by designed questionnaires.The contents of investigation included： general condition of infants and their parents,health condition in pregnancy in mothers,abortion and artificial labor in mothers.Associations between the risk factors studied and low birth weight were analyzed with Logistic regression.Results After adjusting Region,nation and other factors,maternal hypertension,parity more than one,mature were all associated with low birth weight（P0.01）,and the odds ratios（95%CI）of low birth weight associated with the clustering of premature,parity,maternal hypertension,anemia were 6.311（95%CI 5.024～7.926）,27.49（95%CI 19.80～38.18）,35.04（95%CI 15.66～78.40）,compared with non-existence of the risk factor.Odds ratios of the clustering of two risk factors or more were all more than that of one risk factor.Conclusion The risk of low birth weight increased with the number of clustering of risk factors in China.
出处
《苏州大学学报（医学版）》
CAS
北大核心
2011年第5期747-750,754,共5页
Suzhou University Journal of Medical Science
基金
中央级公益性科研院所基本科研业务费专项重点专项(2007GJSSJKA05)
关键词
低出生体质量
危险因素
聚集关联性
low birth weight
risk factors
clustering and association
