摘要
目的了解医院感染铜绿假单胞菌临床科室分布及耐药趋势,为临床合理选用抗菌药提供依据。方法铜绿假单胞菌培养与鉴定按照《全国临床检验操作规程》进行,药敏试验采用K-B纸片扩散法。结果 62株铜绿假单胞菌主要分布在呼吸科、神经外科、血液科,分别占37.10%、16.13%、16.13%;耐药率>50.00%的抗菌药物为头孢曲松、头孢噻肟、环丙沙星、磺胺甲噁唑/甲氧苄啶;头孢哌酮/舒巴坦最敏感,敏感率为96.77%;亚胺培南、阿米卡星、哌拉西林/他唑巴坦、头孢哌酮、头孢他啶,敏感率>80.00%;哌拉西林、头孢吡肟、左氧氟沙星、氨曲南,敏感率>70.00%。结论铜绿假单胞菌已有明显耐药趋势,应加强监测与控制。
OBJECTIVE To learn the clinical distribution and the drug resistance developing tendency of the nosocomial Pseudomonad aeruginosa infection,to provide the basis for clinics to select antibiotics reasonably. METHODS PAE was cultured and identified according to the National Clinical Laboratory Operation Rules.The drug sensitivity was performed by K-B methods. RESULTS Totally 62 strains of P.aeruginosa mainly in the respiratory（37.10%）,neurosurgery（16.13%）,hematology（16.13%）;the susceptibility test showed that resistance rates to ceftriaxone,cefotaxime,ciprofloxacin,sulfamethoxazole/trimethoprim were above 50.00%;cefoperazone/sulbactam was with the highest sensitivity rate（96.77%）;the sensitivity rates to imipenem,amikacin,piperacillin/tazobactam,cefoperazone,and ceftazidime were above 80.00%;the sensitivity rates to piperacillin,ceftazidime,levofloxacin,and aztreonam were above 70.00%. CONCLUSION P.aeruginosa has had an significant resistance trend,the monitoring and control of which should be strengthened.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2011年第23期5061-5062,共2页
Chinese Journal of Nosocomiology
关键词
铜绿假单胞菌
医院感染
耐药性
Pseudomonas aeruginosa
Nosocomial infection
Drug resistance
