摘要
目的探讨医院重症监护病房(ICU)中288株鲍氏不动杆菌(ABA)的耐药性,为临床医师合理用药提供科学的试验依据。方法 ABA分离、鉴定严格按照《全国临床检验操作规程》进行;药敏试验采用K-B法,依据CLSI 2009-2010年折点判读结果。结果 ICU中ABA在呼吸道标本中检出率占首位,达70.1%;ABA对临床常用抗菌药物均产生了不同程度的耐药性,对亚胺培南和美罗培南耐药率分别达到34.0%和33.3%;ICU分离的ABA中,泛耐药菌株检出率为16.7%。结论应加强对多药耐药ABA的动态监测,预防ABA医院感染暴发流行。
OBJECTIVE To approach the antimicrobial resistance of 288 isolates of Acinetobacter baumannii（ABA） in intensive care unit to provide the scientific evidence for clinically reasonable use of antibiotics. METHODS Referring to National Guide to Clinical Laboratory Operation Procedures,ABA were isolated and identified.The susceptibility testing was performed by K-B methods.The testing results were read according to CLSI 2009-2010. RESULTS Most of the isolates came from respiratory tract（70.1%）.The susceptibility results showed ABA had been resistant to commonly used antibiotics in different degrees.The resistance rates of imipenem and meropenem arrived at 34.0% and 33.3%,respectively.The isolating rate of pan-resistant strains from ICU was 16.7%. CONCLUSION Hospitals should strengthen dynamical monitoring of multidrug resistant ABA to prevent the outbreak and prevalence of ABA causing nosocomial infections.
出处
《中华医院感染学杂志》
CAS
CSCD
北大核心
2011年第23期5066-5067,共2页
Chinese Journal of Nosocomiology
关键词
重症监护病房
鲍氏不动杆菌
医院感染
耐药性
Intensive care unit
Acinetobacter baumannii
Nosocomial infection
Antimicrobial resistance
